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The YopJ superfamily in plant-associated bacteria

Lewis JD, Lee A, Ma W, Zhou H, Guttman DS, Desveaux D Mol. Plant Pathol. 2011 Dec;12(9):928-37 PMID: 21726386 Abstract Bacterial pathogens employ the type III secretion system to secrete and translocate effector proteins into their hosts. The primary function of these effector proteins is believed to be the suppression of host defence responses or … Read More

Endogenous GABA(A) and GABA(B) receptor-mediated electrical suppression is critical to neuronal anoxia tolerance

Pamenter ME, Hogg DW, Ormond J, Shin DS, Woodin MA, Buck LT Proc. Natl. Acad. Sci. U.S.A. 2011 Jul;108(27):11274-9 PMID: 21690381 Abstract Anoxic insults cause hyperexcitability and cell death in mammalian neurons. Conversely, in anoxia-tolerant turtle brain, spontaneous electrical activity is suppressed by anoxia (i.e., spike arrest; SA) and cell death does not occur. The … Read More

In Search of Food: Exploring the Evolutionary Link Between cGMP-Dependent Protein Kinase (PKG) and Behaviour

Fitzpatrick MJ, Sokolowski MB Integr. Comp. Biol. 2004 Feb;44(1):28-36 PMID: 21680483 Abstract Despite an immense amount of variation in organisms throughout the animal kingdom many of their genes show substantial conservation in DNA sequence and protein function. Here we explore the potential for a conserved evolutionary relationship between genes and their behavioural phenotypes. We investigate … Read More