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A Par-1-Par-3-Centrosome Cell Polarity Pathway and Its Tuning for Isotropic Cell Adhesion

Jiang T, McKinley RF, McGill MA, Angers S, Harris TJ Curr. Biol. 2015 Oct;25(20):2701-8 PMID: 26455305 Abstract To form regulated barriers between body compartments, epithelial cells polarize into apical and basolateral domains and assemble adherens junctions (AJs). Despite close links with polarity networks that generate single polarized domains, AJs distribute isotropically around the cell circumference … Read More

PARASITIC PLANTS. Probing strigolactone receptors in Striga hermonthica with fluorescence

Tsuchiya Y, Yoshimura M, Sato Y, Kuwata K, Toh S, Holbrook-Smith D, Zhang H, McCourt P, Itami K, Kinoshita T, Hagihara S Science 2015 Aug;349(6250):864-8 PMID: 26293962 Abstract Elucidating the signaling mechanism of strigolactones has been the key to controlling the devastating problem caused by the parasitic plant Striga hermonthica. To overcome the genetic intractability … Read More

Structure-function analysis identifies highly sensitive strigolactone receptors in Striga

Toh S, Holbrook-Smith D, Stogios PJ, Onopriyenko O, Lumba S, Tsuchiya Y, Savchenko A, McCourt P Science 2015 Oct;350(6257):203-7 PMID: 26450211 Abstract Strigolactones are naturally occurring signaling molecules that affect plant development, fungi-plant interactions, and parasitic plant infestations. We characterized the function of 11 strigolactone receptors from the parasitic plant Striga hermonthica using chemical and … Read More