Pubmed Frontpage

50 years of Arabidopsis research: highlights and future directions

October 22, 2015

Provart NJ, Alonso J, Assmann SM, Bergmann D, Brady SM, Brkljacic J, Browse J, Chapple C, Colot V, Cutler S, Dangl J, Ehrhardt D, Friesner JD, Frommer WB, Grotewold E, Meyerowitz E, Nemhauser J, Nordborg M, Pikaard C, Shanklin J, Somerville C, Stitt M, Torii KU, Waese J, Wagner D, McCourt P New Phytol. 2015 … Read More

Sensory-Evoked Spiking Behavior Emerges via an Experience-Dependent Plasticity Mechanism

September 16, 2015

van Rheede JJ, Richards BA, Akerman CJ Neuron 2015 Sep;87(5):1050-62 PMID: 26335647 Abstract The ability to generate action potentials (spikes) in response to synaptic input determines whether a neuron participates in information processing. How a developing neuron becomes an active participant in a circuit or whether this process is activity dependent is not known, especially … Read More

A Sox2 distal enhancer cluster regulates embryonic stem cell differentiation potential

April 10, 2015

Zhou HY, Katsman Y, Dhaliwal NK, Davidson S, Macpherson NN, Sakthidevi M, Collura F, Mitchell JA Genes Dev. 2014 Dec;28(24):2699-711 PMID: 25512558 Abstract The Sox2 transcription factor must be robustly transcribed in embryonic stem (ES) cells to maintain pluripotency. Two gene-proximal enhancers, Sox2 regulatory region 1 (SRR1) and SRR2, display activity in reporter assays, but … Read More