Suzanne Erb

faculty_img Academic Title: Associate Professor

Campus: UTSC

CSB Appointment: Cross Appointment

Primary Undergraduate Department:
Psychology, UTSC

Graduate Programs:
Cell & Systems Biology
Psychology

Titles and Honors:


Academic or Administrative Appointments:


Education:
PhD, Concordia University, 2000
MA, Concordia University, 1996
BSc, Wilfrid Laurier University, 1995

 

Mailing Address
Department of Cell & Systems Biology
University of Toronto
1265 Military Trail
Scarborough, ON M1C 1A4
Canada
 

 

Contact Information
Office phone: 416-287-7454 
Office: SW 531 
Lab:  
Lab phone: 416-287-5612 
Email: erb@utsc.utoronto.ca 
URL: http://www.utsc.utoronto.ca/~erb/

 

Research Areas
Animal Biology
Neurobiology
Psychology & Behavior

 

Research

My general research interests concern the neurobiology of relapse to drug seeking and the interface between neurobiology and behavior in the study of substance abuse. I am particularly interested in how the brain changes at neurotransmitter system and gene expression levels as a consequence of a history of drug exposure, and how these changes are manifest in behavior. Although a number of significant neurobiological changes occur in the early stages of drug withdrawal (first several days), it is the potential for enduring, long-term changes (those that persist or may only emerge after weeks or months of withdrawal), and how these changes may render a former user vulnerable to episodes of relapse, that is of particular interest to me.

 

Publications

2014

Top
Repeated intravenous administrations of teneurin-C terminal associated peptide (TCAP)-1 attenuates reinstatement of cocaine seeking by corticotropin-releasing factor (CRF) in rats.Erb S, McPhee M, Brown ZJ, Kupferschmidt DA, Song L, Lovejoy DA.Behav. Brain Res. 2014 Aug;269:1-5
pubmed
Cocaine exposure prior to pregnancy alters the psychomotor response to cocaine and transcriptional regulation of the dopamine D1 receptor in adult male offspring.Sasaki A, Constantinof A, Pan P, Kupferschmidt DA, McGowan PO, Erb S.Behav. Brain Res. 2014 May;265:163-70
pubmed

2012

Top
Ecologically valid assessment of executive dysfunction using a novel virtual reality task in patients with acquired brain injury.Jovanovski D, Zakzanis K, Ruttan L, Campbell Z, Erb S, Nussbaum D.Appl Neuropsychol Adult 2012;19(3):207-20
pubmed
Development of a novel, ecologically oriented virtual reality measure of executive function: the Multitasking in the City Test.Jovanovski D, Zakzanis K, Campbell Z, Erb S, Nussbaum D.Appl Neuropsychol Adult 2012;19(3):171-82
pubmed
Reinstatement of cocaine seeking in rats by the pharmacological stressors, corticotropin-releasing factor and yohimbine: role for D1/5 dopamine receptors.Brown ZJ, Kupferschmidt DA, Erb S.Psychopharmacology (Berl.) 2012 Dec;224(3):431-40
pubmed
Expression and resilience of a cocaine-conditioned locomotor response after brief and extended drug-free periods.Johnson SA, Sediqzadah S, Erb S.Behav. Brain Res. 2012 Apr;230(1):69-77
pubmed

2011

Top
A procedure for studying the footshock-induced reinstatement of cocaine seeking in laboratory rats.Kupferschmidt DA, Brown ZJ, Erb S.J Vis Exp 2011;(47)
pubmed
Central injections of noradrenaline induce reinstatement of cocaine seeking and increase c-fos mRNA expression in the extended amygdala.Brown ZJ, Nobrega JN, Erb S.Behav. Brain Res. 2011 Mar;217(2):472-6
pubmed
Teneurin C-terminal associated peptide-1 blocks the effects of corticotropin-releasing factor on reinstatement of cocaine seeking and on cocaine-induced behavioural sensitization.Kupferschmidt DA, Lovejoy DA, Rotzinger S, Erb S.Br. J. Pharmacol. 2011 Feb;162(3):574-83
pubmed

2010

Top
Age-related effects of acute nicotine on behavioural and neuronal measures of anxiety.Kupferschmidt DA, Funk D, Erb S, Lê AD.Behav. Brain Res. 2010 Dec;213(2):288-92
pubmed
Evaluation of the relationship between anxiety during withdrawal and stress-induced reinstatement of cocaine seeking.Erb S.Prog. Neuropsychopharmacol. Biol. Psychiatry 2010 Jun;34(5):798-807
pubmed
Role of CRF and other neuropeptides in stress-induced reinstatement of drug seeking.Shalev U, Erb S, Shaham Y.Brain Res. 2010 Feb;1314:15-28
pubmed

2009

Top
Interaction between noradrenaline and corticotrophin-releasing factor in the reinstatement of cocaine seeking in the rat.Brown ZJ, Tribe E, D'souza NA, Erb S.Psychopharmacology (Berl.) 2009 Mar;203(1):121-30
pubmed
Effects of repeated yohimbine on the extinction and reinstatement of cocaine seeking.Kupferschmidt DA, Tribe E, Erb S.Pharmacol. Biochem. Behav. 2009 Jan;91(3):473-80
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2007

Top
Footshock stress reinstates cocaine seeking in rats after extended post-stress delays.Brown ZJ, Erb S.Psychopharmacology (Berl.) 2007 Nov;195(1):61-70
pubmed

2006

Top
A study of the lasting effects of cocaine pre-exposure on anxiety-like behaviors under baseline conditions and in response to central injections of corticotropin-releasing factor.Erb S, Kayyali H, Romero K.Pharmacol. Biochem. Behav. 2006 Sep;85(1):206-13
pubmed
A role for corticotropin-releasing factor in the long-term expression of behavioral sensitization to cocaine.Erb S, Brown ZJ.Behav. Brain Res. 2006 Sep;172(2):360-4
pubmed
Central injections of CRF reinstate cocaine seeking in rats after postinjection delays of up to 3 h: an influence of time and environmental context.Erb S, Petrovic A, Yi D, Kayyali H.Psychopharmacology (Berl.) 2006 Jul;187(1):112-20
pubmed
Effects of central neurokinin-1 receptor antagonism on cocaine- and opiate-induced locomotor activity and self-administration behaviour in rats.Placenza FM, Fletcher PJ, Vaccarino FJ, Erb S.Pharmacol. Biochem. Behav. 2006 May;84(1):94-101
pubmed

2005

Top
Activation of central neurokinin-1 receptors induces reinstatement of cocaine-seeking behavior.Placenza FM, Vaccarino FJ, Fletcher PJ, Erb S.Neurosci. Lett. 2005 Dec;390(1):42-7
pubmed
Activation of central neurotensin receptors reinstates cocaine seeking in the rat: modulation by a D1/D5, but not D2/D3, receptor antagonist.Lopak V, Erb S.Psychopharmacology (Berl.) 2005 Oct;182(2):297-304
pubmed
Cocaine pre-exposure enhances CRF-induced expression of c-fos mRNA in the central nucleus of the amygdala: an effect that parallels the effects of cocaine pre-exposure on CRF-induced locomotor activity.Erb S, Funk D, Lê AD.Neurosci. Lett. 2005 Aug;383(3):209-14
pubmed
Neurocognitive deficits in cocaine users: a quantitative review of the evidence.Jovanovski D, Erb S, Zakzanis KK.J Clin Exp Neuropsychol 2005 Feb;27(2):189-204
pubmed

2003

Top
Prior, repeated exposure to cocaine potentiates locomotor responsivity to central injections of corticotropin-releasing factor (CRF) in rats.Erb S, Funk D, Lê AD.Psychopharmacology (Berl.) 2003 Dec;170(4):383-9
pubmed