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UID:3@csb.utoronto.ca
DTSTART;TZID=America/Toronto:20251024T110000
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DTSTAMP:20251006T190650Z
URL:https://csb.utoronto.ca/events/csb-seminar-david-bilder-phd-uc-berkele
 y/
SUMMARY:CSB Seminar: David Bilder\, PhD - UC Berkeley
DESCRIPTION:CSB Departmental Seminar\nFriday\, October 24th @ 11:00 am\nSPE
 AKER: David Bilder\, PhD - UC Berkeley\nTITLE: Invertebrate oncology: tumo
 r-host interactions in the Drosophila model\nABSTRACT: \nThere is a large
  gap between the deep understanding of mechanisms driving oncogenic transf
 ormation and the reasons why patients ultimately succumb to cancer. We now
  appreciate that interactions between the tumor and surrounding non-tumor 
 (‘host’) cells play critical roles in mortality as well as tumor progr
 ession\, but many mechanisms remain unknown. Drosophila’s high conservat
 ion of biology and genetics with humans has powered its long track record 
 of high-impact discoveries\; the reductionist fly system is particularly w
 ell-suited to probe mysteries of tumor–host interactions. I will discuss
  our use of Drosophila cancer models to study ‘paraneoplasias’ such as
  cachexia\, coagulopathy\, and fluid dysregulation\, and will present unpu
 blished work on anti-tumor immunity and immune evasion in this experimenta
 lly tractable invertebrate.\nHOST: Ulli Tepass\nLOCATION: Cell and System
 s Biology\, 25 Harbord Street\, Suite 432\nLIVESTREAM LINK: https://csb.u
 toronto.ca/live-stream/
CATEGORIES:seminar
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