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UID:31@csb.utoronto.ca
DTSTART;TZID=America/Toronto:20260116T110000
DTEND;TZID=America/Toronto:20260116T120000
DTSTAMP:20251215T155142Z
URL:https://csb.utoronto.ca/events/owen-tamplin-phd-department-of-cell-and
 -regenerative-biology-university-of-wisconsin-madison-csb-seminar/
SUMMARY:Owen Tamplin\, PhD - Department of Cell and Regenerative Biology\, 
 University of Wisconsin - Madison  -- CSB Seminar
DESCRIPTION:CSB Departmental Seminar\nFriday\, January 16th @ 11:00 am\nSPE
 AKER: Owen Tamplin\, PhD - Department of Cell and Regenerative Biology\, U
 niversity of Wisconsin - Madison\nTITLE: The blood stem cell microenvironm
 ent: development and function across the lifespan\nABSTRACT: Our lab prima
 rily focuses on understanding the hematopoietic stem cell (HSC) niche micr
 oenvironment. HSC transplantation is a curative treatment for many blood d
 iseases and cancers\, however\, many of these procedures still fail and th
 ere is a need to improve success rates. Therefore\, a better understanding
  of the signals and adhesion molecules in the HSC microenvironment that re
 gulate engraftment of HSCs after transplantation\, and maintain HSCs in an
  undifferentiated state\, are critical for improving clinical HSC therapie
 s. Our lab uses complementary zebrafish and mouse models for in vivo cell 
 biology and translational studies\, respectively. We integrate cutting-edg
 e technologies to gain new perspectives on the HSC microenvironment. We ar
 e focused on three main areas of research: 1) Understanding the emergence 
 and migration of HSCs between different sites of hematopoiesis in the embr
 yo\; 2) Defining the role of neurotransmitters and metabolites in the HSC 
 niche\; 3) Generating new animal models for the study of development and d
 isease.\n\nHOST: Felix Gunawan\nLOCATION: Cell and Systems Biology\, 25 H
 arbord Street\, Suite 432\nLIVESTREAM LINK: https://csb.utoronto.ca/live-
 stream/
CATEGORIES:seminar
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