Tod Thiele
Assistant Professor
Campus
UTSC
CSB Appointment
Full
Research Areas
Neurobiology, Systems Biology
Education
University of Oregon Ph.D. in Biology 2007
Hamilton College BA in Biology 1999
Primary Undergraduate Department
Biological Sciences, UTSC
Graduate Programs
Cell & Systems Biology
Neuroscience
Research Description
Our research uses zebrafish to investigate how neural circuits control behaviour. To gain insights into neural circuit function we use a combination of behavioural analyses, calcium imaging, optogenetics and genome engineering.
Contact Information
Office Phone: 416-287-7035
Office: SW421E
Email
Mailing Address
Department of Cell & Systems Biology
University of Toronto
1265 Military Trail
Scarborough, ON M1C 1A4
Canada
Publications
2023
The mesencephalic locomotor region recruits V2a reticulospinal neurons to drive forward locomotion in larval zebrafish.
Carbo-Tano M, Lapoix M, Jia X, Thouvenin O, Pascucci M, Auclair F, Quan FB, Albadri S, Aguda V, Farouj Y, Hillman EMC, Portugues R, Del Bene F, Thiele TR, Dubuc R, Wyart C
2023, Nature neuroscience, 37667039
Spatiotemporal visual statistics of aquatic environments in the natural habitats of zebrafish
Cai LT, Krishna VS, Hladnik TC, Guilbeault NC, Vijayakumar C, Arunachalam M, Juntti SA, Arrenberg AB, Thiele TR, Cooper EA
2023, Scientific Reports, 10.1038/s41598-023-36099-z
2022
Optic flow in the natural habitats of zebrafish supports spatial biases in visual self-motion estimation
Alexander E, Cai LT, Fuchs S, Hladnik TC, Zhang Y, Subramanian V, Guilbeault NC, Vijayakumar C, Arunachalam M, Juntti SA, Thiele TR, Arrenberg AB, Cooper EA
2022, Current Biology, 10.1016/j.cub.2022.10.009
2021
BonZeb: open-source, modular software tools for high-resolution zebrafish tracking and analysis
Guilbeault NC, Guerguiev J, Martin M, Tate I, Thiele TR
2021, Scientific Reports, 10.1038/s41598-021-85896-x
Manipulation of the Tyrosinase gene permits improved CRISPR/Cas editing and neural imaging in cichlid fish
Li C, Steighner JR, Sweatt G, Thiele TR, Juntti SA
2021, Scientific Reports, 10.1038/s41598-021-94577-8
2020
Parallel Channels for Motion Feature Extraction in the Pretectum and Tectum of Larval Zebrafish
Wang K, Hinz J, Zhang Y, Thiele TR, Arrenberg AB
2020, Cell Reports, 10.1016/j.celrep.2019.12.031
2014
A dedicated visual pathway for prey detection in larval zebrafish
Semmelhack JL, Donovan JC, Thiele TR, Kuehn E, Laurell E, Baier H
2014, eLife, 3, 25490154
Descending control of swim posture by a midbrain nucleus in zebrafish
Thiele TR, Donovan JC, Baier H
2014, Neuron, 83, 679-91, 25066082
2011
An image-free opto-mechanical system for creating virtual environments and imaging neuronal activity in freely moving Caenorhabditis elegans
Faumont S, Rondeau G, Thiele TR, Lawton KJ, McCormick KE, Sottile M, Griesbeck O, Heckscher ES, Roberts WM, Doe CQ, Lockery SR
2011, PloS one, 6, e24666, 21969859
Optogenetic analysis of synaptic transmission in the central nervous system of the nematode Caenorhabditis elegans
Lindsay TH, Thiele TR, Lockery SR
2011, Nature communications, 2, 306, 21556060
2009
The neural network for chemotaxis to tastants in Caenorhabditis elegans is specialized for temporal differentiation
Thiele TR, Faumont S, Lockery SR
2009, The Journal of neuroscience : the official journal of the Society for Neuroscience, 29, 11904-11, 19776276
2008
Functional asymmetry in Caenorhabditis elegans taste neurons and its computational role in chemotaxis
Suzuki H, Thiele TR, Faumont S, Ezcurra M, Lockery SR, Schafer WR
2008, Nature, 454, 114-7, 18596810
Artificial dirt: microfluidic substrates for nematode neurobiology and behavior
Lockery SR, Lawton KJ, Doll JC, Faumont S, Coulthard SM, Thiele TR, Chronis N, McCormick KE, Goodman MB, Pruitt BL
2008, Journal of neurophysiology, 99, 3136-43, 18337372
2005
Step-response analysis of chemotaxis in Caenorhabditis elegans
Miller AC, Thiele TR, Faumont S, Moravec ML, Lockery SR
2005, The Journal of neuroscience : the official journal of the Society for Neuroscience, 25, 3369-78, 15800192
2004
Natural variation in the npr-1 gene modifies ethanol responses of wild strains of C. elegans
Davies AG, Bettinger JC, Thiele TR, Judy ME, McIntire SL
2004, Neuron, 42, 731-43, 15182714