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The molecular biology revolution has given us the unprecedented ability to explore fundamental mechanisms that govern life. Researchers in the Department of Cell & Systems Biology work to understand these mechanisms at all levels of biological organization using a wide array of state-of-the-art molecular, genomic, proteomic, cell biological, imaging, physiological and computational tools and methods.
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New & Noteworthy Publications
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- The Receptor Kinases BAK1/SERK4 Regulate Ca2+ Channel-Mediated Cellular Homeostasis for Cell Death Containment. Yu X, Xu G, Li B, de Souza Vespoli L, Liu H, Moeder W, Chen S, de Oliveira MVV, Ariádina de Souza S, Shao W, Rodrigues B, Ma Y, Chhajed S, Xue S, Berkowitz GA, Yoshioka K, He P, Shan L, Current Biology. 2019 Nov 18;29(22):3778-3790.e8.
- Apical polarity proteins recruit the RhoGEF Cysts to promote junctional myosin assembly. Silver JT, Wirtz-Peitz F, Simões S, Pellikka M, Yan D, Binari R, Nishimura T, Li Y, Harris TJC, Perrimon N, Tepass U, J Cell Biol. 2019 Oct 7;218(10):3397-3414.
- Recurrent non-coding U1-snRNA mutations drive cryptic splicing in Shh medulloblastoma. Suzuki H, Kumar SA, Shuai S, […] Calarco JA, Stein L, Taylor MD, Nature. 2019;574:707–711.
- High Temporal-Resolution Transcriptome Landscape of Early Maize Seed Development Yi F, Gu W, Chen J, Song N, Gao X, Zhang X, Zhou Y, Ma X, Song W, Zhao H, Esteban E, Pasha A, Provart NJ, Lai J, Plant Cell. 2019 May;31(5):974-992.
- A cargo model of yolk syncytial nuclear migration during zebrafish epiboly. Fei Z, Bae K, Parent SE, Wan H, Goodwin K, Theisen U, Tanentzapf G, Bruce AEE, Development. 2019 Jan 2;146(1). [Video summary of this paper]
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