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The molecular biology revolution has given us the unprecedented ability to explore fundamental mechanisms that govern life. Researchers in the Department of Cell & Systems Biology work to understand these mechanisms at all levels of biological organization using a wide array of state-of-the-art molecular, genomic, proteomic, cell biological, imaging, physiological and computational tools and methods.
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New & Noteworthy Publications
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- SMAX1-dependent seed germination bypasses GA signalling in Arabidopsis and Striga. Bunsick M, Toh S, Wong C, Xu Z, Ly G, McErlean CSP, Pescetto G, Nemrish KE, Sung P, Li JD, Scholes JD, Lumba S, Nature Plants. 2020 May. [CSB News Story] [News & Views]
- Cortical interneuron-mediated inhibition delays the onset of amyotrophic lateral sclerosis. Khademullah CS, Aqrabawi AJ, Place KM, Dargaei Z, Liang X, Pressey JC, Bedard S, Yang JW, Garand D, Keramidis I, Gasecka A, Côté D, De Koninck Y, Keith J, Zinman L, Robertson J, Kim JC, Woodin MA, Brain. 2020 Mar 143;3:800-810. [UofT News Story]
- The Receptor Kinases BAK1/SERK4 Regulate Ca2+ Channel-Mediated Cellular Homeostasis for Cell Death Containment. Yu X, Xu G, Li B, de Souza Vespoli L, Liu H, Moeder W, Chen S, de Oliveira MVV, Ariádina de Souza S, Shao W, Rodrigues B, Ma Y, Chhajed S, Xue S, Berkowitz GA, Yoshioka K, He P, Shan L, Current Biology. 2019 Nov 18;29(22):3778-3790.e8.
- Apical polarity proteins recruit the RhoGEF Cysts to promote junctional myosin assembly. Silver JT, Wirtz-Peitz F, Simões S, Pellikka M, Yan D, Binari R, Nishimura T, Li Y, Harris TJC, Perrimon N, Tepass U, J Cell Biol. 2019 Oct 7;218(10):3397-3414.
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