New and Noteworthy Publications

Transcriptional regulation and chromatin architecture maintenance are decoupled functions at the Sox2 locus.

Taylor T, Sikorska N, Shchuka VM, Chahar S, Ji C, Macpherson NN, Moorthy SD, de Kort MAC, Mullany S, Khader N, Gillespie ZE, Langroudi L, Tobias IC, Lenstra TL, Mitchell JA, Sexton T
2022, Genes & development, 35710138

Idiosyncratic epistasis leads to global fitness–correlated trends

Bakerlee CW, Nguyen Ba AN, Shulgina Y, Rojas Echenique JI, Desai MM
2022, Science, 10.1126/science.abm4774

Autophagy is required for self-incompatible pollen rejection in two transgenic Arabidopsis thaliana accessions

Macgregor SR, Lee HK, Nelles H, Johnson DC, Zhang T, Ma C, Goring DR
2022, Plant Physiology, 10.1093/plphys/kiac026

Elevated tyrosine results in the cytosolic retention of 3‐deoxy‐ d ‐arabino‐heptulosonate 7‐phosphate synthase in Arabidopsis thaliana

Kanaris M, Poulin J, Shahinas D, Johnson D, Crowley VM, Fucile G, Provart N, Christendat D
2021, The Plant Journal, 10.1111/tpj.15590

Usher syndrome type 1-associated gene, pcdh15b, is required for photoreceptor structural integrity in zebrafish

Miles A, Blair C, Emili A, Tropepe V
2021, Disease Models & Mechanisms, 10.1242/dmm.048965

Force-dependent activation of actin elongation factor mDia1 protects the cytoskeleton from mechanical damage and promotes stress fiber repair

Valencia FR, Sandoval E, Du J, Iu E, Liu J, Plotnikov SV
2021, Developmental Cell, 10.1016/j.devcel.2021.11.004

p38-mediated cell growth and survival drive rapid embryonic wound repair

Scepanovic G, Hunter MV, Kafri R, Fernandez-Gonzalez R
2021, Cell Reports, 10.1016/j.celrep.2021.109874

Simultaneous expression of UV and violet SWS1 opsins expands the visual palette in a group of freshwater snakes

Hauzman E, Pierotti MER, Bhattacharyya N, Tashiro JH, Yovanovich CAM, Campos PF, Ventura DF, Chang BSW, Yoder A
2021, Molecular Biology and Evolution, 10.1093/molbev/msab285

Cell–cell contact landscapes in Xenopus gastrula tissues

Barua D, Nagel M, Winklbauer R
2021, Proceedings of the National Academy of Sciences, 10.1073/pnas.2107953118

Multiple phosphorylation events of the mitochondrial membrane protein, TTM1, regulate cell death during senescence

Karia P, Yoshioka K, Moeder W
2021, The Plant Journal, 10.1111/tpj.15470

Three mutations repurpose a plant karrikin receptor to a strigolactone receptor

Arellano-Saab A, Bunsick M, Al Galib H, Zhao W, Schuetz S, Bradley JM, Xu Z, Adityani C, Subha A, McKay H, de Saint Germain A, Boyer F, McErlean CSP, Toh S, McCourt P, Stogios PJ, Lumba S
2021, Proceedings of the National Academy of Sciences, 10.1073/pnas.2103175118

Self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease

Scott BM, Gutiérrez-Vázquez C, Sanmarco LM, da Silva Pereira JA, Li Z, Plasencia A, Hewson P, Cox LM, O’Brien M, Chen SK, Moraes-Vieira PM, Chang BSW, Peisajovich SG, Quintana FJ
2021, Nature Medicine, 10.1038/s41591-021-01390-x

Capillarity and active cell movement at mesendoderm translocation in the Xenopus gastrula

Nagel M, Barua D, Damm EW, Kashef J, Hofmann R, Ershov A, Cecilia A, Moosmann J, Baumbach T, Winklbauer R
2021, Development, 10.1242/dev.198960

Recreated Ancestral Opsin Associated with Marine to Freshwater Croaker Invasion Reveals Kinetic and Spectral Adaptation

Van Nynatten A, Castiglione GM, de A. Gutierrez E, Lovejoy NR, Chang BSW
2021, Molecular Biology and Evolution, 10.1093/molbev/msab008

Conserved biophysical features of the CaV2 presynaptic Ca2+ channel homologue from the early-diverging animal Trichoplax adhaerens

Gauberg J, Abdallah S, Elkhatib W, Harracksingh AN, Piekut T, Stanley EF, Senatore A
2020, Journal of Biological Chemistry, 10.1074/jbc.RA120.015725

Global regulatory features of alternative splicing across tissues and within the nervous system of C. elegans

Koterniak B, Pilaka PP, Gracida X, Schneider L, Pritišanac I, Zhang Y, Calarco JA
2020, Genome Research, 10.1101/gr.267328.120

EPSIN1 and MTV1 define functionally overlapping but molecularly distinct trans-Golgi network subdomains in Arabidopsis

Heinze L, Freimuth N, Rößling A, Hahnke R, Riebschläger S, Fröhlich A, Sampathkumar A, McFarlane HE, Sauer M
2020, Proceedings of the National Academy of Sciences, 10.1073/pnas.2004822117

Integration of Migratory Cells into a New Site In Vivo Requires Channel-Independent Functions of Innexins on Microtubules

Miao G, Godt D, Montell DJ
2020, Developmental Cell, 10.1016/j.devcel.2020.06.024

The pan-genome effector-triggered immunity landscape of a host-pathogen interaction

Laflamme B, Dillon MM, Martel A, Almeida RND, Desveaux D, Guttman DS
2020, Science, 10.1126/science.aax4079

Enhancer-gene rewiring in the pathogenesis of Quebec platelet disorder.

Liang M, Soomro A, Tasneem S, Abatti LE, Alizada A, Yuan X, Uusküla-Reimand L, Antounians L, Alvi SA, Paterson AD, Rivard GÉ, Scott IC, Mitchell JA, Hayward CPM, Wilson MD
2020, Blood, 136, 2679-2690, 32663239

Cortical interneuron-mediated inhibition delays the onset of amyotrophic lateral sclerosis

Woodin MA, Kim JC, Robertson J, Zinman L, Keith J, De Koninck Y, Côté D, Gasecka A, Keramidis I, Garand D, Yang JW, Bedard S, Pressey JC, Liang X, Dargaei Z, Place KM, Aqrabawi AJ, Khademullah CS
2020, Brain, 10.1093/brain/awaa034

Spatiotemporal Restriction of FUSCA3 Expression by Class I BPCs Promotes Ovule Development and Coordinates Embryo and Endosperm Growth

Wu J, Mohamed D, Dowhanik S, Petrella R, Gregis V, Li J, Wu L, Gazzarrini S
2020, The Plant Cell, 10.1105/tpc.19.00764

Par-1 controls the composition and growth of cortical actin caps during Drosophila embryo cleavage

Harris TJ, Jiang T
2019, Journal of Cell Biology, 10.1083/jcb.201903152

The Sublaterodorsal Tegmental Nucleus Functions to Couple Brain State and Motor Activity during REM Sleep and Wakefulness

Torontali ZA, Fraigne JJ, Sanghera P, Horner R, Peever J
2019, Current Biology, 10.1016/j.cub.2019.09.026