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CSB Seminar: Professor Sara Aton, Molecular, Cellular and Developmental Biology, University of Michigan

October 14, 2016 @ 2:00 pm - 3:00 pm

Cell & Systems Biology
Departmental Seminar

Prof. Sara Aton
Molecular, Cellular & Developmental Biology
University of Michigan

“Network Oscillations Coordinate Neuronal Ensembles
during Sleep-dependent Memory Consolidation

Host:  Prof. John Peever <john.peever@utoronto.ca>

A major feature of mammalian sleep is the presence of low-frequency oscillations
of highly synchronous activity between the cortex and thalamus, and between
thalamocortical circuits and the hippocampus. We find that consolidation of fear
memories and consolidation of plasticity in the visual system are blocked by disruption
of these sleep-dependent oscillations (in hippocampal and thalmocortical circuits, respectively)
in the hours following a learning experience. Our current data suggest that network oscillations
are necessary to promote the stable reactivation of neuronal ensembles, which in turn drives
long-term memory storage across brain circuits.

Video Conferencing at UTM (DV3138) & UTSc (MW229)


October 14, 2016
2:00 pm - 3:00 pm
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Ramsay Wright Building, Room 432
25 Harbord St.
Toronto, ON M5S 3G5 Canada