Research in our department investigates the behaviour of cells – the fundamental units of life – in terms of molecular processes within and between cells. Both hypothesis-driven and discovery-based strategies are integrated to gain a mechanistic understanding of complex and highly dynamic cellular systems and how they govern the development, physiology, and evolution of organisms.

CSB embraces new methodologies and state-of-the art technologies. Its researchers use a wide range of cutting-edge tools to study the fundamental biological mechanisms that govern interactions at all levels of complexity, ranging from molecules to communities.

CSB has particular expertise in high-throughput functional genomics, structural and chemical biology, advanced imaging, computational, and physiological approaches. Our research also makes use of a variety of model prokaryotic and eukaryotic organisms and cultured mammalian cells, including stem cell models of differentiation.

Please select one of our research themes below to explore our diverse faculty and research programs!

Recent Publications

GABA neurons in the sublaterodorsal tegmental nucleus suppress wakefulness in healthy and narcoleptic mice

Csicsvari J, Lee H, Fraigne JJ, Peever JH
2026, PLOS Biology, 10.1371/journal.pbio.3003303

Ubiquitination of the ribosomal-like domain of UBIQUITIN6 contributes to cell wall stress responses in Arabidopsis

Zhu Y, Ramírez Rodríguez EA, Chow F, Azad FT, McNally U, Kang HS, Ebert B, McFarlane HE
2026, The Plant Cell, 10.1093/plcell/koag187

An in vivo parallelized reporter assay to uncover tissue-specific splicing regulatory sequences in a multicellular animal

Bhatnagar S, Ho J, Sadek NH, Singh I, Zoberman M, Koterniak B, Liu Y, Fusca DD, Cutter AD, Moses AM, Calarco J
2026, Nucleic Acids Research, 10.1093/nar/gkag451

All Publications

Latest News

Summer at the lab bench yields stunning breakthroughs and earns prizes

We were excited to see this year's crop of summer students present the fruits of their research at the 2026 Summer undergraduate poster session.…

Nyman Scholarship earned by paying it forward in research and student life

Gretl Baghdadi has earned the 2026 Dr Leslie Paul Nyman Scholarship for her commitment to plant biology, her academic excellence and her support of…

CSB researchers identify nerve cells that trigger sleep and help balance waking and sleeping states

Researchers from the University of Toronto have identified a "switch" in the brains of mice that, when activated, induces sleep and acts in balance…

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