Research in our department investigates the behaviour of cells – the fundamental units of life – in terms of molecular processes within and between cells. Both hypothesis-driven and discovery-based strategies are integrated to gain a mechanistic understanding of complex and highly dynamic cellular systems and how they govern the development, physiology, and evolution of organisms.
CSB embraces new methodologies and state-of-the art technologies. Its researchers use a wide range of cutting-edge tools to study the fundamental biological mechanisms that govern interactions at all levels of complexity, ranging from molecules to communities.
CSB has particular expertise in high-throughput functional genomics, structural and chemical biology, advanced imaging, computational, and physiological approaches. Our research also makes use of a variety of model prokaryotic and eukaryotic organisms and cultured mammalian cells, including stem cell models of differentiation.
Please select one of our research themes below to explore our diverse faculty and research programs!
Recent Publications
GABA neurons in the sublaterodorsal tegmental nucleus suppress wakefulness in healthy and narcoleptic mice
Csicsvari J, Lee H, Fraigne JJ, Peever JH
2026, PLOS Biology, 10.1371/journal.pbio.3003303
Ubiquitination of the ribosomal-like domain of UBIQUITIN6 contributes to cell wall stress responses in Arabidopsis
Zhu Y, Ramírez Rodríguez EA, Chow F, Azad FT, McNally U, Kang HS, Ebert B, McFarlane HE
2026, The Plant Cell, 10.1093/plcell/koag187
An in vivo parallelized reporter assay to uncover tissue-specific splicing regulatory sequences in a multicellular animal
Bhatnagar S, Ho J, Sadek NH, Singh I, Zoberman M, Koterniak B, Liu Y, Fusca DD, Cutter AD, Moses AM, Calarco J
2026, Nucleic Acids Research, 10.1093/nar/gkag451
Latest News
CSB researchers identify nerve cells that trigger sleep and help balance waking and sleeping states
August 21, 2026
Researchers from the University of Toronto have identified a "switch" in the brains of mice that, when activated, induces sleep and acts in balance…
Nelson Award for outstanding research impact to Prof Heather McFarlane
August 12, 2026
Congratulation to Professor Heather McFarlane, who has earned the C.D. Nelson Award from the Canadian Society of Plant Biologists (CSPB) for "an…
Pulling a ring on it: Camsap2 protein leads to tension in zebrafish embryos by coordinating distinct pathways
August 10, 2026
A surprising insight into the impressive architecture of developing embryos is revealed in a new paper in Development by researchers in CSB.…





