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CSB Seminar Series – Tanya Svitkina- University of Pennsylvania
April 14, 2023 @ 11:00 am - 12:00 pm
CSB Departmental Seminar
Professor Tanya Svitkina
Department of Biology, University of Pennsylvania
TITLE: Distinct and collective roles of different cytoskeletal machineries in cells
ABSTRACT: My laboratory investigates roles of the actin cytoskeleton in various cellular activities, such as cell motility, morphogenesis, cell shape determination, cell-cell interactions and membrane organelle dynamics. Our distinctive approach toward this goal is to use platinum replica electron microscopy (PREM) to determine high resolution structure of the cytoskeleton and combine it with more conventional approaches to study dynamics of the cell, cellular organelles, or specific proteins. I will present our recent and new findings on (i) the role of microtubules in regulating assembly of branched actin networks, (ii) cytoskeletal mechanisms of clathrin-mediated endocytosis and (iii) cooperation of different paralogs of nonmuscle myosin II during assembly of the cellular contractile system.
HOST: Sergey Plotnikov
LOCATION: Cell and Systems Biology, 25 Harbord Street, Suite 432
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