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CSB Special Seminar: Dr. Gregory Emery, IRIC-University of Montreal

August 18, 2015 @ 2:00 pm - 3:00 pm

CSB Special Seminar

Dr. Gregory Emery
IRIC-University of Montreal

“An Interplay between 14-3-3 and the Rab11 Binding Potein Rip11 is Necessary for the Completion of Cytokinesis”

During cell division, the site of cytokinesis has to be precisely defined to ensure normal mitosis. In recent years, our understanding of the mechanisms ensuring the proper distribution of the cytokinetic machinery has significantly improved, yet the role and regulation of several molecules of the vesicular trafficking machinery in establishing the cytokinesis furrow and the abscission site is still under investigation. Here we have identify an interaction between 14-3-3 and Rip11, the sole Drosophila ortholog of the Rab11 class I family of effectors (Rab11-FIP1, 2 and 5), and we have found that it plays an important role in the distribution of key regulators of cytokinesis. In addition, recent developments concerning our work on the regulation of cell-cell communication during collective cell migration will also be discussed.
Host:  Prof. Dorothea Godt  < d.godt@utoronto.ca>


August 18, 2015
2:00 pm - 3:00 pm
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Ramsay Wright Building, Room 432
25 Harbord St.
Toronto, ON M5S 3G5 Canada