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MSc Exit Seminar – Noushin Koulena (Desveaux lab)
September 18, 2015 @ 10:00 am - 10:30 am
MSc Exit Seminar
Friday September 18th, 10:10 am – Ramsay Wright Building, Rm. 432
Noushin Koulena (Desveaux lab)
“Functional Characterization of the HopF Family of Type III Effectors in Arabidopsis thaliana“
Abstract
Pseudomonas syringae is a Gram-negative bacterial phytopathogen that causes disease in economically important crops. An essential virulence strategy of P. syringae involves injecting type III secretion effectors (T3SEs) into host cells to inhibit immune signaling. Advances in genomic sequencing have led to an increase in the available number of sequences of plant bacterial pathogens, which has led to identification of divergent homologs of known T3SEs. The HopF family of T3SE contains over 40 diverse family members. In order to explore the functional diversification of HopF family, this thesis undertakes the functional characterization of HopF T3SE in Arabidopsis thaliana. Functional analysis revealed multiple members with novel immune responses in Arabidopsis. A reverse genetics approach was used to identify the mechanism underlying the novel immune responses triggered by HopF family of T3SE. The Arabidopsis R protein ZAR1 was required for recognition of a novel member of the HopF family.
Ramsay Wright is a wheelchair accessible building.