Adam Mott

Assistant Professor


Campus

UTSC

CSB Appointment

Full

Research Areas

Evolutionary Biology, Microbiology, Molecular Biology, Plant Biology, Systems Biology

Education

Ph.D. Harvard University, 2008
B.Sc. University of British Columbia, 2001

Primary Undergraduate Department

Biological Sciences, UTSC

Graduate Programs

Cell & Systems Biology

Research Description

We combine wet lab and computational approaches to study how plants use cell surface receptors to sense their environment, integrate this information, and regulate growth and immunity.


Contact Information

Office Phone: 416-287-7427
Office: SY264
Lab: SY270 Lab 1
Email

Mailing Address

Department of Cell & Systems Biology
University of Toronto
1265 Military Trail
Scarborough, ON M1C 1A4
Canada

Visit lab’s website


Publications

2019

Map of physical interactions between extracellular domains of Arabidopsis leucine-rich repeat receptor kinases

Mott GA, Smakowska-Luzan E, Pasha A, Parys K, Howton TC, Neuhold J, Lehner A, Grünwald K, Stolt-Bergner P, Provart NJ, Mukhtar MS, Desveaux D, Guttman DS, Belkhadir Y
2019, Scientific Data, 10.1038/sdata.2019.25

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2018

A High-Sensitivity, Microtiter-Based Plate Assay for Plant Pattern-Triggered Immunity.

Mott GA, Desveaux D, Guttman DS
2018, Molecular plant-microbe interactions : MPMI, 31, 499-504, 29199888

An extracellular network of Arabidopsis leucine-rich repeat receptor kinases.

Smakowska-Luzan E, Mott GA, Parys K, Stegmann M, Howton TC, Layeghifard M, Neuhold J, Lehner A, Kong J, Grünwald K, Weinberger N, Satbhai SB, Mayer D, Busch W, Madalinski M, Stolt-Bergner P, Provart NJ, Mukhtar MS, Zipfel C, Desveaux D, Guttman DS, Belkhadir Y
2018, Nature, 553, 342-346, 29320478

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2017

An Alternative Strategy for Trypanosome Survival in the Mammalian Bloodstream Revealed through Genome and Transcriptome Analysis of the Ubiquitous Bovine Parasite Trypanosoma (Megatrypanum) theileri.

Kelly S, Ivens A, Mott GA, O\'Neill E, Emms D, Macleod O, Voorheis P, Tyler K, Clark M, Matthews J, Matthews K, Carrington M
2017, Genome biology and evolution, 9, 2093-2109, 28903536

The study of pattern-triggered immunity in Arabidopsis

Mott GA, Guttman DS, Desveaux D
2017, Canadian Journal of Plant Pathology, 10.1080/07060661.2017.1355850

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2016

Genomic screens identify a new phytobacterial microbe-associated molecular pattern and the cognate Arabidopsis receptor-like kinase that mediates its immune elicitation.

Mott GA, Thakur S, Smakowska E, Wang PW, Belkhadir Y, Desveaux D, Guttman DS
2016, Genome biology, 17, 98, 27160854

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2014

Immunomodulation by the Pseudomonas syringae HopZ type III effector family in Arabidopsis.

Lewis JD, Wilton M, Mott GA, Lu W, Hassan JA, Guttman DS, Desveaux D
2014, PloS one, 9, e116152, 25546415

The Pseudomonas syringae type III effector HopF2 suppresses Arabidopsis stomatal immunity.

Hurley B, Lee D, Mott A, Wilton M, Liu J, Liu YC, Angers S, Coaker G, Guttman DS, Desveaux D
2014, PloS one, 9, e114921, 25503437

Peptides and small molecules of the plant-pathogen apoplastic arena.

Mott GA, Middleton MA, Desveaux D, Guttman DS
2014, Frontiers in plant science, 5, 677, 25506352

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2011

Targeting cattle-borne zoonoses and cattle pathogens using a novel trypanosomatid-based delivery system.

Mott GA, Wilson R, Fernando A, Robinson A, MacGregor P, Kennedy D, Schaap D, Matthews JB, Matthews KR
2011, PLoS pathogens, 7, e1002340, 22046137

A soluble factor from Trypanosoma cruzi inhibits transforming growth factor-ß-induced MAP kinase activation and gene expression in dermal fibroblasts.

Mott GA, Costales JA, Burleigh BA
2011, PloS one, 6, e23482, 21931601

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2009

Modulation of host cell mechanics by Trypanosoma cruzi.

Mott A, Lenormand G, Costales J, Fredberg JJ, Burleigh BA
2009, Journal of cellular physiology, 218, 315-22, 18853412

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2008

The role of host cell lysosomes in Trypanosoma cruzi invasion.

Mott GA, Burleigh BA
2008, Sub-cellular biochemistry, 47, 165-73, 18512350

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