Bebhinn Treanor
Associate Professor
Campus
UTSC
CSB Appointment
Full
Research Areas
Cell Biology
Primary Undergraduate Department
Biological Sciences, UTSC
Research Description
My research focuses on the cellular and molecular mechanisms controlling immune cell activation through the development and implementation of cutting edge optical microscopy.
Contact Information
Office Phone: 416-208-2926
Office: SW567
Email
Mailing Address
Department of Cell & Systems Biology
University of Toronto
1265 Military Trail
Scarborough, ON M1C 1A4
Canada
Publications
2013
The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling
Mattila PK, Feest C, Depoil D, Treanor B, Montaner B, Otipoby KL, Carter R, Justement LB, Bruckbauer A, Batista FD
2013, Immunity, 38, 461-74, 23499492
2012
2011
Editorial: Counting the carbs: a memory B cell makeover
Treanor B, Cancro MP
2011, Journal of leukocyte biology, 90, 1-3, 21719461
Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity
Treanor B, Depoil D, Bruckbauer A, Batista FD
2011, The Journal of experimental medicine, 208, 1055-68, 21482698
2010
Visualizing a role for the actin cytoskeleton in the regulation of B-cell activation
Batista FD, Treanor B, Harwood NE
2010, Immunological reviews, 237, 191-204, 20727037
Organisation and dynamics of antigen receptors: implications for lymphocyte signalling
Treanor B, Batista FD
2010, Current opinion in immunology, 22, 299-307, 20434893
The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor
Treanor B, Depoil D, Gonzalez-Granja A, Barral P, Weber M, Dushek O, Bruckbauer A, Batista FD
2010, Immunity, 32, 187-99, 20171124
2009
Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production
Randall KL, Lambe T, Johnson AL, Johnson A, Treanor B, Kucharska E, Domaschenz H, Whittle B, Tze LE, Enders A, Crockford TL, Bouriez-Jones T, Alston D, Cyster JG, Lenardo MJ, Mackay F, Deenick EK, Tangye SG, Chan TD, Camidge T, Brink R, Vinuesa CG, Batista FD, Cornall RJ, Goodnow CC
2009, Nature immunology, 10, 1283-91, 19898472
Microsignalosomes: spatially resolved receptor signalling
Treanor B, Harwood NE, Batista FD
2009, Biochemical Society transactions, 37, 1014-8, 19754442
Early events of B cell activation by antigen
Depoil D, Weber M, Treanor B, Fleire SJ, Carrasco YR, Harwood NE, Batista FD
2009, Science signaling, 2, pt1, 19318623
2008
Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen
Weber M, Treanor B, Depoil D, Shinohara H, Harwood NE, Hikida M, Kurosaki T, Batista FD
2008, The Journal of experimental medicine, 205, 853-68, 18362175
2007
CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand
Depoil D, Fleire S, Treanor BL, Weber M, Harwood NE, Marchbank KL, Tybulewicz VL, Batista FD
2008, Nature immunology, 9, 63-72, 18059271
The role of integrins and coreceptors in refining thresholds for B-cell responses
Batista FD, Arana E, Barral P, Carrasco YR, Depoil D, Eckl-Dorna J, Fleire S, Howe K, Vehlow A, Weber M, Treanor B
2007, Immunological reviews, 218, 197-213, 17624954
Mechanistic insight into lymphocyte activation through quantitative imaging and theoretical modelling
Treanor B, Batista FD
2007, Current opinion in immunology, 19, 476-83, 17659866
2006
Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses
Treanor B, Lanigan PM, Kumar S, Dunsby C, Munro I, Auksorius E, Culley FJ, Purbhoo MA, Phillips D, Neil MA, Burshtyn DN, French PM, Davis DM
2006, The Journal of cell biology, 174, 153-61, 16801390
2004
Time-domain fluorescence lifetime imaging applied to biological tissue
Elson D, Requejo-Isidro J, Munro I, Reavell F, Siegel J, Suhling K, Tadrous P, Benninger R, Lanigan P, McGinty J, Talbot C, Treanor B, Webb S, Sandison A, Wallace A, Davis D, Lever J, Neil M, Phillips D, Stamp G, French P
2004, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 3, 795-801, 15295637