Bebhinn Treanor

Associate Professor



CSB Appointment


Research Areas

Cell Biology

Primary Undergraduate Department

Biological Sciences, UTSC

Research Description

My research focuses on the cellular and molecular mechanisms controlling immune cell activation through the development and implementation of cutting edge optical microscopy.

Contact Information

Office Phone: 416-208-2926
Office: SW567

Mailing Address

Department of Cell & Systems Biology
University of Toronto
1265 Military Trail
Scarborough, ON M1C 1A4



The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling

Mattila PK, Feest C, Depoil D, Treanor B, Montaner B, Otipoby KL, Carter R, Justement LB, Bruckbauer A, Batista FD
2013, Immunity, 38, 461-74, 23499492

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B-cell receptor: from resting state to activate

Treanor B
2012, Immunology, 136, 21-7, 22269039

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Editorial: Counting the carbs: a memory B cell makeover

Treanor B, Cancro MP
2011, Journal of leukocyte biology, 90, 1-3, 21719461

Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity

Treanor B, Depoil D, Bruckbauer A, Batista FD
2011, The Journal of experimental medicine, 208, 1055-68, 21482698

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Visualizing a role for the actin cytoskeleton in the regulation of B-cell activation

Batista FD, Treanor B, Harwood NE
2010, Immunological reviews, 237, 191-204, 20727037

Organisation and dynamics of antigen receptors: implications for lymphocyte signalling

Treanor B, Batista FD
2010, Current opinion in immunology, 22, 299-307, 20434893

The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor

Treanor B, Depoil D, Gonzalez-Granja A, Barral P, Weber M, Dushek O, Bruckbauer A, Batista FD
2010, Immunity, 32, 187-99, 20171124

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Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

Randall KL, Lambe T, Johnson AL, Johnson A, Treanor B, Kucharska E, Domaschenz H, Whittle B, Tze LE, Enders A, Crockford TL, Bouriez-Jones T, Alston D, Cyster JG, Lenardo MJ, Mackay F, Deenick EK, Tangye SG, Chan TD, Camidge T, Brink R, Vinuesa CG, Batista FD, Cornall RJ, Goodnow CC
2009, Nature immunology, 10, 1283-91, 19898472

Microsignalosomes: spatially resolved receptor signalling

Treanor B, Harwood NE, Batista FD
2009, Biochemical Society transactions, 37, 1014-8, 19754442

Early events of B cell activation by antigen

Depoil D, Weber M, Treanor B, Fleire SJ, Carrasco YR, Harwood NE, Batista FD
2009, Science signaling, 2, pt1, 19318623

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Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen

Weber M, Treanor B, Depoil D, Shinohara H, Harwood NE, Hikida M, Kurosaki T, Batista FD
2008, The Journal of experimental medicine, 205, 853-68, 18362175

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CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand

Depoil D, Fleire S, Treanor BL, Weber M, Harwood NE, Marchbank KL, Tybulewicz VL, Batista FD
2008, Nature immunology, 9, 63-72, 18059271

The role of integrins and coreceptors in refining thresholds for B-cell responses

Batista FD, Arana E, Barral P, Carrasco YR, Depoil D, Eckl-Dorna J, Fleire S, Howe K, Vehlow A, Weber M, Treanor B
2007, Immunological reviews, 218, 197-213, 17624954

Mechanistic insight into lymphocyte activation through quantitative imaging and theoretical modelling

Treanor B, Batista FD
2007, Current opinion in immunology, 19, 476-83, 17659866

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Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses

Treanor B, Lanigan PM, Kumar S, Dunsby C, Munro I, Auksorius E, Culley FJ, Purbhoo MA, Phillips D, Neil MA, Burshtyn DN, French PM, Davis DM
2006, The Journal of cell biology, 174, 153-61, 16801390

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Time-domain fluorescence lifetime imaging applied to biological tissue

Elson D, Requejo-Isidro J, Munro I, Reavell F, Siegel J, Suhling K, Tadrous P, Benninger R, Lanigan P, McGinty J, Talbot C, Treanor B, Webb S, Sandison A, Wallace A, Davis D, Lever J, Neil M, Phillips D, Stamp G, French P
2004, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 3, 795-801, 15295637

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