Bryan Stewart
Professor
Campus
UTM
CSB Appointment
Full
Research Areas
Animal Biology, Neurobiology, Physiology
Primary Undergraduate Department
Biology, UTM
Graduate Programs
Cell & Systems Biology
Research Description
Our research is aimed at understanding the cellular and molecular mechanisms that govern the function and development of neurons. We use a variety of genetic, molecular, biochemical, imaging and physiological techniques aimed at determining how neurons communicate with other cells.
Contact Information
Office Phone: DV3266
Lab: DV2023
Lab Phone: 905-569-4304
Email
Mailing Address
Department of Biology
University of Toronto
3359 Mississauga Road
Mississauga, ON L5L 1C6
Canada
Publications
2014
Investigation of the juxtamembrane region of neuronal-Synaptobrevin in synaptic transmission at the Drosophila neuromuscular junction
DeMill CM, Qiu X, Kisiel M, Bolotta A, Stewart BA
2014, Journal of neurophysiology, 24944220
Localization and Mobility of Synaptic Vesicles in Myosin VI Mutants of Drosophila
Kisiel M, McKenzie K, Stewart B
2014, PloS one, 9, e102988, 25062032
Second harmonic generation polarization properties of myofilaments
Samim M, Prent N, Dicenzo D, Stewart B, Barzda V
2014, Journal of biomedical optics, 19, 056005, 24805809
Drosophila SNAP-29 is an essential SNARE that binds multiple proteins involved in membrane traffic
Xu H, Mohtashami M, Stewart B, Boulianne G, Trimble WS
2014, PloS one, 9, e91471, 24626111
2013
Early consolidation of development and physiology of an identified presynaptic nerve terminal
Laviolette M, Stewart BA
2013, BMC neuroscience, 14, 124, 24134061
2012
Effect of juxtamembrane tryptophans on the immersion depth of Synaptobrevin, an integral vesicle membrane protein
Al-Abdul-Wahid MS, Demill CM, Serwin MB, Prosser RS, Stewart BA
2012, Biochimica et biophysica acta, 1818, 2994-9, 22846509
2011
Myosin VI contributes to synaptic transmission and development at the Drosophila neuromuscular junction
Kisiel M, Majumdar D, Campbell S, Stewart BA
2011, BMC neuroscience, 12, 65, 21745401
Synaptic transmission and plasticity are modulated by nonmuscle myosin II at the neuromuscular junction of Drosophila
Seabrooke S, Stewart BA
2011, Journal of neurophysiology, 105, 1966-76, 21325687
2010
Nonmuscle Myosin II helps regulate synaptic vesicle mobility at the Drosophila neuromuscular junction
Seabrooke S, Qiu X, Stewart BA
2010, BMC neuroscience, 11, 37, 20233422
2008
Moesin helps to restrain synaptic growth at the Drosophila neuromuscular junction
Seabrooke S, Stewart BA
2008, Developmental neurobiology, 68, 379-91, 18161855
2007
Dystroglycan and protein O-mannosyltransferases 1 and 2 are required to maintain integrity of Drosophila larval muscles
Haines N, Seabrooke S, Stewart BA
2007, Molecular biology of the cell, 18, 4721-30, 17881734
2006
Functional roles for beta1,4-N-acetlygalactosaminyltransferase-A in Drosophila larval neurons and muscles
Haines N, Stewart BA
2007, Genetics, 175, 671-9, 17151241
Interaction of cytoskeleton genes with NSF2-induced neuromuscular junction overgrowth
Peyre JB, Seabrooke S, Randlett O, Kisiel M, Aigaki T, Stewart BA
2006, Genesis (New York, N.Y. : 2000), 44, 595-600, 17139674
Synaptic vesicle mobility and presynaptic F-actin are disrupted in a N-ethylmaleimide-sensitive factor allele of Drosophila
Nunes P, Haines N, Kuppuswamy V, Fleet DJ, Stewart BA
2006, Molecular biology of the cell, 17, 4709-19, 16914524
2005
Disruption of synaptic development and ultrastructure by Drosophila NSF2 alleles
Stewart BA, Pearce J, Bajec M, Khorana R
2005, The Journal of comparative neurology, 488, 101-11, 15912502
A genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth
Laviolette MJ, Nunes P, Peyre JB, Aigaki T, Stewart BA
2005, Genetics, 170, 779-92, 15834148
2004
Population density regulates Drosophila synaptic morphology in a Fasciclin-II-dependent manner
Stewart BA, McLean JR
2004, Journal of neurobiology, 61, 392-9, 15490479
2002
Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viability
Bhattacharya S, Stewart BA, Niemeyer BA, Burgess RW, McCabe BD, Lin P, Boulianne G, O'Kane CJ, Schwarz TL
2002, Proceedings of the National Academy of Sciences of the United States of America, 99, 13867-72, 12364587
A Drosophila SNAP-25 null mutant reveals context-dependent redundancy with SNAP-24 in neurotransmission
Vilinsky I, Stewart BA, Drummond J, Robinson I, Deitcher DL
2002, Genetics, 162, 259-71, 12242238
Dominant-negative NSF2 disrupts the structure and function of Drosophila neuromuscular synapses
Stewart BA, Mohtashami M, Rivlin P, Deitcher DL, Trimble WS, Boulianne GL
2002, Journal of neurobiology, 51, 261-71, 12150502
Membrane trafficking in Drosophila wing and eye development
Stewart BA
2002, Seminars in cell & developmental biology, 13, 91-7, 12127141