Professor Bryan Stewart

Bryan Stewart




CSB Appointment


Research Areas

Animal Biology, Neurobiology, Physiology

Primary Undergraduate Department

Biology, UTM

Graduate Programs

Cell & Systems Biology

Research Description

Our research is aimed at understanding the cellular and molecular mechanisms that govern the function and development of neurons. We use a variety of genetic, molecular, biochemical, imaging and physiological techniques aimed at determining how neurons communicate with other cells.

Contact Information

Office Phone: DV3266
Lab: DV2023
Lab Phone: 905-569-4304

Mailing Address

Department of Biology
University of Toronto
3359 Mississauga Road
Mississauga, ON L5L 1C6

Visit lab’s website



Investigation of the juxtamembrane region of neuronal-Synaptobrevin in synaptic transmission at the Drosophila neuromuscular junction

DeMill CM, Qiu X, Kisiel M, Bolotta A, Stewart BA
2014, Journal of neurophysiology, 24944220

Localization and Mobility of Synaptic Vesicles in Myosin VI Mutants of Drosophila

Kisiel M, McKenzie K, Stewart B
2014, PloS one, 9, e102988, 25062032

Second harmonic generation polarization properties of myofilaments

Samim M, Prent N, Dicenzo D, Stewart B, Barzda V
2014, Journal of biomedical optics, 19, 056005, 24805809

Drosophila SNAP-29 is an essential SNARE that binds multiple proteins involved in membrane traffic

Xu H, Mohtashami M, Stewart B, Boulianne G, Trimble WS
2014, PloS one, 9, e91471, 24626111

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Early consolidation of development and physiology of an identified presynaptic nerve terminal

Laviolette M, Stewart BA
2013, BMC neuroscience, 14, 124, 24134061

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Effect of juxtamembrane tryptophans on the immersion depth of Synaptobrevin, an integral vesicle membrane protein

Al-Abdul-Wahid MS, Demill CM, Serwin MB, Prosser RS, Stewart BA
2012, Biochimica et biophysica acta, 1818, 2994-9, 22846509

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Myosin VI contributes to synaptic transmission and development at the Drosophila neuromuscular junction

Kisiel M, Majumdar D, Campbell S, Stewart BA
2011, BMC neuroscience, 12, 65, 21745401

Synaptic transmission and plasticity are modulated by nonmuscle myosin II at the neuromuscular junction of Drosophila

Seabrooke S, Stewart BA
2011, Journal of neurophysiology, 105, 1966-76, 21325687

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Nonmuscle Myosin II helps regulate synaptic vesicle mobility at the Drosophila neuromuscular junction

Seabrooke S, Qiu X, Stewart BA
2010, BMC neuroscience, 11, 37, 20233422

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Moesin helps to restrain synaptic growth at the Drosophila neuromuscular junction

Seabrooke S, Stewart BA
2008, Developmental neurobiology, 68, 379-91, 18161855

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Dystroglycan and protein O-mannosyltransferases 1 and 2 are required to maintain integrity of Drosophila larval muscles

Haines N, Seabrooke S, Stewart BA
2007, Molecular biology of the cell, 18, 4721-30, 17881734

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Functional roles for beta1,4-N-acetlygalactosaminyltransferase-A in Drosophila larval neurons and muscles

Haines N, Stewart BA
2007, Genetics, 175, 671-9, 17151241

Interaction of cytoskeleton genes with NSF2-induced neuromuscular junction overgrowth

Peyre JB, Seabrooke S, Randlett O, Kisiel M, Aigaki T, Stewart BA
2006, Genesis (New York, N.Y. : 2000), 44, 595-600, 17139674

Synaptic vesicle mobility and presynaptic F-actin are disrupted in a N-ethylmaleimide-sensitive factor allele of Drosophila

Nunes P, Haines N, Kuppuswamy V, Fleet DJ, Stewart BA
2006, Molecular biology of the cell, 17, 4709-19, 16914524

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Disruption of synaptic development and ultrastructure by Drosophila NSF2 alleles

Stewart BA, Pearce J, Bajec M, Khorana R
2005, The Journal of comparative neurology, 488, 101-11, 15912502

A genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth

Laviolette MJ, Nunes P, Peyre JB, Aigaki T, Stewart BA
2005, Genetics, 170, 779-92, 15834148

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Population density regulates Drosophila synaptic morphology in a Fasciclin-II-dependent manner

Stewart BA, McLean JR
2004, Journal of neurobiology, 61, 392-9, 15490479

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Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viability

Bhattacharya S, Stewart BA, Niemeyer BA, Burgess RW, McCabe BD, Lin P, Boulianne G, O'Kane CJ, Schwarz TL
2002, Proceedings of the National Academy of Sciences of the United States of America, 99, 13867-72, 12364587

A Drosophila SNAP-25 null mutant reveals context-dependent redundancy with SNAP-24 in neurotransmission

Vilinsky I, Stewart BA, Drummond J, Robinson I, Deitcher DL
2002, Genetics, 162, 259-71, 12242238

Dominant-negative NSF2 disrupts the structure and function of Drosophila neuromuscular synapses

Stewart BA, Mohtashami M, Rivlin P, Deitcher DL, Trimble WS, Boulianne GL
2002, Journal of neurobiology, 51, 261-71, 12150502

Membrane trafficking in Drosophila wing and eye development

Stewart BA
2002, Seminars in cell & developmental biology, 13, 91-7, 12127141

Introduction: membrane trafficking, secretion and development

Stewart BA
2002, Seminars in cell & developmental biology, 13, 69-70, 12127137

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