Rongmin Zhao

Associate Professor



CSB Appointment


Research Areas

Developmental Biology, Molecular Biology, Physiology, Plant Biology, Proteomics, Systems Biology


Ph.D. Chinese Academy of Agricultural Sciences 1995
BSc, Peking University 1991

Primary Undergraduate Department

Biological Sciences, UTSC

Graduate Programs

Cell & Systems Biology

Research Description

The mechanism of action of molecular chaperones and their roles in plant development, and in organelle functions; the mechanism of regulated protein degradation by the 26S proteasome.

Contact Information

Office Phone: 416-208-2740
Office: SY248
Lab: SY215
Lab Phone: 416-208-2741

Mailing Address

Department of Cell & Systems Biology
University of Toronto
1265 Military Trail
Scarborough, ON M1C 1A4

Visit lab’s website



A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis

Zhang M, Wang C, Lin Q, Liu A, Wang T, Feng X, Liu J, Han H, Ma Y, Bonea D, Zhao R, Hua X
2015, The Plant journal : for cell and molecular biology, 83, 582-599, 26072661

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A highly charged region in the middle domain of plant endoplasmic reticulum (ER)-localized heat-shock protein 90 is required for resistance to tunicamycin or high calcium-induced ER stresses

Chong LP, Wang Y, Gad N, Anderson N, Shah B, Zhao R
2015, Journal of experimental botany, 66, 113-24, 25297550

Cosuppression of the chloroplast localized molecular chaperone HSP90.5 impairs plant development and chloroplast biogenesis in Arabidopsis

Oh SE, Yeung C, Babaei-Rad R, Zhao R
2014, BMC research notes, 7, 643, 25216779

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The stability of the small nucleolar ribonucleoprotein (snoRNP) assembly protein Pih1 in Saccharomyces cerevisiae is modulated by its C terminus

Paci A, Liu XH, Huang H, Lim A, Houry WA, Zhao R
2012, The Journal of biological chemistry, 287, 43205-14, 23139418

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Structure of minimal tetratricopeptide repeat domain protein Tah1 reveals mechanism of its interaction with Pih1 and Hsp90

Jiménez B, Ugwu F, Zhao R, Ortí L, Makhnevych T, Pineda-Lucena A, Houry WA
2012, The Journal of biological chemistry, 287, 5698-709, 22179618

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Expression of five AtHsp90 genes in Saccharomyces cerevisiae reveals functional differences of AtHsp90s under abiotic stresses

Song H, Fan P, Shi W, Zhao R, Li Y
2010, Journal of plant physiology, 167, 1172-8, 20493581

Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity

Zhao R, Leung E, Grüner S, Schapira M, Houry WA
2010, PloS one, 5, e9934, 20376192

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Overexpression of AtHsp90.2, AtHsp90.5 and AtHsp90.7 in Arabidopsis thaliana enhances plant sensitivity to salt and drought stresses

Song H, Zhao R, Fan P, Wang X, Chen X, Li Y
2009, Planta, 229, 955-64, 19148673

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Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation

Zhao R, Kakihara Y, Gribun A, Huen J, Yang G, Khanna M, Costanzo M, Brost RL, Boone C, Hughes TR, Yip CM, Houry WA
2008, The Journal of cell biology, 180, 563-78, 18268103

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Expression of a constitutively activated plasma membrane H+-ATPase alters plant development and increases salt tolerance

Gévaudant F, Duby G, von Stedingk E, Zhao R, Morsomme P, Boutry M
2007, Plant physiology, 144, 1763-76, 17600134

Molecular interaction network of the Hsp90 chaperone system

Zhao R, Houry WA
2007, Advances in experimental medicine and biology, 594, 27-36, 17205672

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Specificity in substrate and cofactor recognition by the N-terminal domain of the chaperone ClpX

Thibault G, Yudin J, Wong P, Tsitrin V, Sprangers R, Zhao R, Houry WA
2006, Proceedings of the National Academy of Sciences of the United States of America, 103, 17724-9, 17090685

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Hsp90: a chaperone for protein folding and gene regulation

Zhao R, Houry WA
2005, Biochemistry and cell biology = Biochimie et biologie cellulaire, 83, 703-10, 16333321

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone

Zhao R, Davey M, Hsu YC, Kaplanek P, Tong A, Parsons AB, Krogan N, Cagney G, Mai D, Greenblatt J, Boone C, Emili A, Houry WA
2005, Cell, 120, 715-27, 15766533

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