Satyaki Rajavasireddy

Assistant Professor



CSB Appointment


Research Areas

Bioinformatics / Computational Biology, Biotechnology, Developmental Biology, Evolutionary Biology, Genetics / Genomics, Molecular Biology, Plant Biology


B.S. Osmania Univeristy, India
M.S. Tata Institute for Fundamental Research, India
Ph.D. from Cornell University

Primary Undergraduate Department

Department of Biological Sciences, UTSC

Graduate Programs

Cell and Systems Biology, Ecology and Evolutionary Biology

Research Description

The long-term goal of our lab is to engineer seeds that are adapted to the fast-changing climate of our planet.

Towards this end, we will be studying seed development with a special emphasis on the endosperm. Endosperm is often essential for seed development and provides more than 60% of humanity’s nutritional needs. Unfortunately, endosperm development is sensitive to environmental stress and climate change induced extreme weather can decimate plant productivity.

To engineer resilient seeds, we need a better understanding of seed development. We will use genetic and genomic tools to identify genetic and epigenetic pathways regulating endosperm development in the model organism A. thaliana. However, seed development evolves rapidly and can sometimes vary between even closely related species. Therefore, to obtain a broader perspective into seed development and in order to translate our work into ecologically and environmentally important species, we will examine how and why the regulation of endosperm development changes between species. Using these perspectives, we will examine how endosperm development changes in response to climate change and engineer climate-change tolerant seeds.

Contact Information

Office: SY246
Lab: SY235

Mailing Address

Department of Biological Sciences
University of Toronto
1265 Military Trail
Scarborough, ON M1C 1A4

Visit lab’s website



RNA Pol IV induces antagonistic parent-of-origin effects on Arabidopsis endosperm

Chen X, Satyaki PRV, Gehring M
2022, PLOS Biology, 10.1371/journal.pbio.3001602

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Water lily ( Nymphaea thermarum ) genome reveals variable genomic signatures of ancient vascular cambium losses

Povilus RA, DaCosta JM, Grassa C, Satyaki PRV, Moeglein M, Jaenisch J, Xi Z, Mathews S, Gehring M, Davis CC, Friedman WE
2020, Proceedings of the National Academy of Sciences, 10.1073/pnas.1922873117

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Paternally Acting Canonical RNA-Directed DNA Methylation Pathway Genes Sensitize Arabidopsis Endosperm to Paternal Genome Dosage

Satyaki PR, Gehring M
2019, The Plant Cell, 10.1105/tpc.19.00047

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A variably imprinted epiallele impacts seed development

Köhler C, Pignatta D, Novitzky K, Satyaki PRV, Gehring M
2018, PLOS Genetics, 10.1371/journal.pgen.1007469

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DNA methylation and imprinting in plants: machinery and mechanisms

Satyaki PRV, Gehring M
2017, Critical Reviews in Biochemistry and Molecular Biology, 10.1080/10409238.2017.1279119

A Small RNA Pathway Mediates Allelic Dosage in Endosperm

Erdmann RM, Satyaki PR, Klosinska M, Gehring M
2017, Cell Reports, 10.1016/j.celrep.2017.11.078

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Endosperm and Imprinting, Inextricably Linked

Gehring M, Satyaki P
2016, Plant Physiology, 10.1104/pp.16.01353

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The Hmr and Lhr Hybrid Incompatibility Genes Suppress a Broad Range of Heterochromatic Repeats

Malik HS, Satyaki PRV, Cuykendall TN, Wei KH, Brideau NJ, Kwak H, Aruna S, Ferree PM, Ji S, Barbash DA
2014, PLoS Genetics, 10.1371/journal.pgen.1004240

A Screen for F1 Hybrid Male Rescue Reveals No Major-Effect Hybrid Lethality Loci in theDrosophila melanogasterAutosomal Genome

Cuykendall TN, Satyaki P, Ji S, Clay DM, Edelman NB, Kimchy A, Li L, Nuzzo EA, Parekh N, Park S, Barbash DA
2014, G3 Genes|Genomes|Genetics, 10.1534/g3.114.014076

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How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways

Ferree PM, Prasad S
2012, Genetics Research International, 10.1155/2012/430136

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Lhx2 Selector Activity Specifies Cortical Identity and Suppresses Hippocampal Organizer Fate

Mangale VS, Hirokawa KE, Satyaki PRV, Gokulchandran N, Chikbire S, Subramanian L, Shetty AS, Martynoga B, Paul J, Mai MV, Li Y, Flanagan LA, Tole S, Monuki ES
2008, Science, 10.1126/science.1151695

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