Course Description
Students in BIO255H1F will attend the same lectures as students taking BIO230H1F (see calendar for description of lecture component of BIO230H). The Enhanced Laboratory provides the opportunity for greater laboratory skill development in modern investigative techniques and is intended for students interested in conducting their own laboratory research. Students will attend 10 weekly laboratories.
Please make sure you attend your first lab. There are no alternative or make-up labs for this course. Please bring the notes for Lab 1, a lab coat, safety glasses, and a notebook (Any kind of notebook is fine, but if you intend to print out the lab notes from the course website, a binder with loose leaf paper may be most convenient). Demand for the course may be high, so if you miss the first lab, we cannot guarantee your place in the course.
A very general outline of the lecture and laboratory topics is listed below:
Lecture Topics and Laboratory Exercises
- Sept-Oct
Lecture Topics: Genome biology, regulation of gene expression, regulation of gene product function and location.
Laboratory Exercises: Arabidopsis DNA extraction, basic and more advanced bioinformatics, experimental design, PCR, cloning, plasmid preps, and restriction enzyme diagnostics - Nov-Dec
Lecture Topics: Cell signaling, molecular basis of development and cancer
Laboratory Exercises: Use of immunofluorescence and transgenic Drosophila to examine cell structure and function. Cell imaging and analysis. Primary paper analysis.
Prerequisite
BIO130H1,
CHM (135H1, 136H1) / (138H1, 139H1) / 151Y1,
cGPA 3.0
Exclusion
BIO230H1
Recommended preparation
BCH210H1 (taken concurrently or previously)
Ancillary Fees
This course has a lab fee of $51.
Lab coat and safety glasses are required and the approximate cost is $26. Students are responsible for purchasing these items.
Lecturer(s)
Prof. K. Yip (Day)
Prof. H. McFarlane (Day)
Evening Lecturer: Prof. K. Yip
Course and Laboratory Coordinator
Dr. A. Caragea
Course Administrator
BIO255 Office
Elly Chen
RW206A
416-978-6442
bio255.csb@utoronto.ca
Course Hours
36L, 33P
Required Text(s)/Readings
The required textbook for BIO255H1F 2023 is an e-text rental derived from: Alberts, B., Heald, R., Johnson, A., Morgan, D. O., Raff, M. C., Roberts, K., and Walter, P. (2022). Molecular biology of the cell, 7th edition, New York, NY: W. W. Norton & Company.
Lab Manual
All lab notes will be available on-line through the course Quercus site (will be opened up in late August/early September) for students to view.
Evaluation (Subject to change)
The finalized course evaluation will be posted on Quercus in early September:
October term test (20%)
December final exam (40%)
Lab reports/lab participation/lab and textbook quizzes (40%)
Last updated on July 17th, 2023