Course Description

You are a highly organized collection of functionally diverse cells that were derived from a single fertilized egg. The fundamental question of development is how differences arise between cells and tissues in the embryo. In a common analogy used to describe development, embryonic cells read and execute developmental programs that are stored in their DNA. How can a biologist gain access to these programs in order to dissect and understand them?

This course approaches the problem of development from both a descriptive and experimental point-of-view. Examples will be drawn from the most intensively investigated organisms, including both invertebrates and vertebrates. These embryos are amenable to a wide range of experimental manipulations of their tissues, cells, and molecules. We will explore the major events leading to the formation of the embryo, and examine how various experimental manipulations help to define the mechanisms involved in generating different cell types and embryonic structures.

The course will be presented in two lectures and two tutorial/practical hours each week. The tutorials/practicals will be used in a variety of ways. In some, you will examine living and fixed embryos related to the lectures. In others, you will present seminars and discuss relevant journal articles.

Prerequisites

BIO230H1 / BIO255H1,
BIO260H1 / HMB 265H1

Ancillary Fees

There is a lab fee of $25.

Lecturer(s)

Prof. A. Bruce
ashley.bruce@utoronto.ca
TBA

Contact Hours

24L, 24P

Evaluation (Subject to change)

Mid‑term test: 30%
Final exam: 40%
Tutorial assignments: 30%

Last updated on May 18th, 2021