Course Description

This course examines the molecular and cellular basis of neurogenesis in the developing and adult nervous system. Experimental evidence from recent studies in selected vertebrate model systems will be discussed. Topics include neural stem cells, regional specialization of neurogenesis, neuronal and glial differentiation, extrinsic regulation of neurogenesis, adult neurogenesis, and the evolution of neurogenesis. Students are expected to have a basic knowledge of molecular genetics, developmental biology and/or neuroanatomy. Lectures will be complemented by student directed seminar presentations that focus on specialized research studies published in leading scientific journals (worth 30% of final grade). Critical analysis of primary research is emphasized in this course and will be further evaluated through a midterm essay assignment (worth 30% of final grade) and class discussions (class participation worth 10% of final grade). A final exam will cover material presented in lectures and student presentations (worth 30% of final grade).

Prerequisite

BIO260H1 / HMB265H1,

CSB328H1 / CSB349H1 / (HMB200H1, HMB320H1)

Lecturer(s)

Prof. V. Tropepe
v.tropepe@utoronto.ca

Not Offered

CSB430H1 is not offered in 2022-23.

Contact Hours

24L, 12T

Last updated on May 31st, 2022