CSB Deptl Seminar: Prof. Tobias Meyer, Chemical and Systems Biology, School of Medicine, Stanford University

“Molecular Mechanisms of Polarization and Cell Guidance for Collective Migration”

Friday, September 16, 2016
Ramsay Wright Building, Room 432 at 2 p.m.

Host:  Sergey Plotnikov <sergey.plotnikov@utoronto.ca>

Abstract
I will be presenting our recent work on how cells coordinate their cytoskeletal and signaling machineries to be able to collectively migrate. Particularly, we have been employing live cell imaging and a HUVEC endothelial cell model to understand cell polarization and guidance. I will focus my talk on an intriguing discovery we made of an engulfed tubular structure “cadherin fingers” that have a critical role in cell guidance and the coordination of collective migration.