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CSB Seminar: Prof. J. Todd Blankenship, Director, Molecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver

January 20, 2017 @ 2:00 pm - 3:00 pm

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Departmental Seminar

Prof. J. Todd Blankenship
Director, Molecular and Cellular Biophysics Programs
Department of Biological Sciences
University of Denver

Membrane-dependent cell ratcheting and tissue morphogenesis”

Host:  Prof. Tony Harris <tony.harris@utoronto.ca>

The control of cell shape is a fundamental property required for epithelial tissue architecture and function. Tensile actomyosin forces have been conventionally thought to drive changes in epithelial cell shape and tissue remodeling. However, here we have examined the coordination of membrane trafficking and cytoskeletal networks to direct progressive changes in cell shape. We show that the AP Patterning system engages a membranous ratchet at the plasma membrane to effect interface contraction during cell intercalation. Our results suggest that endocytic and cytoskeletal forces converge on compartmental behaviors to direct cell shaping events.

Video Conferencing at UTM (DV3138) & UTSc (MW229)


January 20, 2017
2:00 pm - 3:00 pm
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Ramsay Wright Building, Room 432
25 Harbord St.
Toronto, ON M5S 3G5 Canada