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CSB Seminar Series – Ovijit Chaudhuri – Stanford University
March 25, 2022 @ 11:00 am - 12:00 pm
TITLE: Extracellular matrix viscoelasticity and its impact on cells
Professor Ovijit Chaudhuri
Department of Mechanical Engineering
Stanford University
The extracellular matrix (ECM) is a complex assembly of structural proteins that provides physical support and biochemical signaling to cells in tissues. Over the last two decades, studies have revealed the important role that ECM elasticity plays in regulating a variety of biological processes in cells, including stem cell differentiation and cancer progression. However, tissues and ECM are often viscoelastic, displaying stress relaxation over time in response to a deformation, and viscoplastic, exhibiting irreversible deformations in response to mechanical stress. In this talk, I will discuss our recent findings on how matrix viscoelasticity regulates various biological processes, including stem cell migration and the morphogenesis of pluripotent stem cells.
HOST: Sergey Plotnikov
Zoom ID and passcode:
https://utoronto.zoom.us/j/87447422547
Meeting ID: 874 4742 2547
Passcode: 050579