Danton H. O’Day

Professor Emeritus


Campus

UTM

CSB Appointment

Emeritus

Research Areas

Cell Biology, Developmental Biology

Education

Ph.D., University of Delaware 1972

Primary Undergraduate Department

Biology, UTM

Graduate Programs

Cell & Systems Biology
Developmental Biology

Research Description

My lab focuses on the role of calmodulin binding proteins in cellular function.


Contact Information

Office Phone: 905-828-3896
Office: DV2003
Lab: DV2016
Lab Phone: 905-828-3897
Email

Mailing Address

Department of Biology
University of Toronto
3359 Mississauga Road
Mississauga, ON L5L 1C6
Canada

Visit lab’s website


Publications

2014

Nucleocytoplasmic protein translocation during mitosis in the social amoebozoan Dictyostelium discoideum

O'Day DH, Budniak A
2014, Biological reviews of the Cambridge Philosophical Society, 24618050

A Lack of Correlation between the Incidence of Lyme Disease and Deaths due to Alzheimer’s Disease

O'Day DH, Catalano A
2014, Journal of Alzheimer's disease : JAD, 42, 115-118, 24840565

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2013

Rad53 homologue forkhead-associated kinase A (FhkA) and Ca2+-binding protein 4a (CBP4a) are nucleolar proteins that differentially redistribute during mitosis in Dictyostelium

Catalano A, O'Day DH
2013, Cell division, 8, 4, 23587254

Matricellular signal transduction involving calmodulin in the social amoebozoan dictyostelium

O'Day DH, Huber RJ
2013, Genes, 4, 33-45, 24705101

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2012

A matricellular protein and EGF-like repeat signalling in the social amoebozoan Dictyostelium discoideum

Huber RJ, O'Day DH
2012, Cellular and molecular life sciences : CMLS, 22782112

Cyclin-dependent kinase 5 is a calmodulin-binding protein that associates with puromycin-sensitive aminopeptidase in the nucleus of Dictyostelium

Huber RJ, Catalano A, O'Day DH
2013, Biochimica et biophysica acta, 1833, 11-20, 23063531

Extracellular calmodulin regulates growth and cAMP-mediated chemotaxis in Dictyostelium discoideum

O'Day DH, Huber RJ, Suarez A
2012, Biochemical and biophysical research communications, 425, 750-4, 22884799

Nucleoplasmic/nucleolar translocation and identification of a nuclear localization signal (NLS) in Dictyostelium BAF60a/SMARCD1 homologue Snf12

Catalano A, O'Day DH
2012, Histochemistry and cell biology, 138, 515-30, 22623154

Ca2+ signaling regulates ecmB expression, cell differentiation and slug regeneration in Dictyostelium

Poloz Y, O'Day DH
2012, Differentiation; research in biological diversity, 84, 163-75, 22595345

EGF-like peptide-enhanced cell movement in Dictyostelium is mediated by protein kinases and the activity of several cytoskeletal proteins

Huber RJ, O'Day DH
2012, Cellular signalling, 24, 1770-80, 22588127

Colchicine affects cell motility, pattern formation and stalk cell differentiation in Dictyostelium by altering calcium signaling

Poloz Y, O'Day DH
2012, Differentiation; research in biological diversity, 83, 185-99, 22381626

The cyclin-dependent kinase inhibitor roscovitine inhibits kinase activity, cell proliferation, multicellular development, and Cdk5 nuclear translocation in Dictyostelium discoideum

Huber RJ, O'Day DH
2012, Journal of cellular biochemistry, 113, 868-76, 22234985

CyrA, a matricellular protein that modulates cell motility in Dictyostelium discoideum

Huber RJ, Suarez A, O'Day DH
2012, Matrix biology : journal of the International Society for Matrix Biology, 31, 271-80, 22391412

Bestatin inhibits cell growth, cell division, and spore cell differentiation in Dictyostelium discoideum

Poloz Y, Catalano A, O'Day DH
2012, Eukaryotic cell, 11, 545-57, 22345351

EGF-like peptide of Dictyostelium discoideum is not a chemoattractant but it does restore folate-mediated chemotaxis in the presence of signal transduction inhibitors

Nikolaeva I, Huber RJ, O'Day DH
2012, Peptides, 34, 145-9, 22234048

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2011

Dictyostelium puromycin-sensitive aminopeptidase A is a nucleoplasmic nucleomorphin-binding protein that relocates to the cytoplasm during mitosis

Catalano A, Poloz Y, O'Day DH
2011, Histochemistry and cell biology, 136, 677-88, 22038042

Signalling and sex in the social amoebozoans

O'Day DH, Keszei A
2012, Biological reviews of the Cambridge Philosophical Society, 87, 313-29, 21929567

Microcysts: the third developmental pathway of social amoebozoans

Budniak AA, O'Day DH
2012, Protist, 163, 2-14, 21798803

Nucleocytoplasmic transfer of cyclin dependent kinase 5 and its binding to puromycin-sensitive aminopeptidase in Dictyostelium discoideum

Huber RJ, O'Day DH
2011, Histochemistry and cell biology, 136, 177-89, 21766205

An extracellular matrix, calmodulin-binding protein from Dictyostelium with EGF-like repeats that enhance cell motility

Suarez A, Huber RJ, Myre MA, O'Day DH
2011, Cellular signalling, 23, 1197-206, 21402150

Nucleolar localization and identification of nuclear/nucleolar localization signals of the calmodulin-binding protein nucleomorphin during growth and mitosis in Dictyostelium

Catalano A, O'Day DH
2011, Histochemistry and cell biology, 135, 239-49, 21327858

Tyrosine phosphorylation of actin during microcyst formation and germination in Polysphondylium pallidum

Budniak A, O'Day DH
2011, Protist, 162, 490-502, 21316301

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2010

EGF-like peptide-enhanced cell motility in Dictyostelium functions independently of the cAMP-mediated pathway and requires active Ca2+/calmodulin signaling

Huber R, O'Day DH
2011, Cellular signalling, 23, 731-8, 21195758

Synthesis and biological activity of peptides equivalent to the IP22 repeat motif found in proteins from Dictyostelium and Mimivirus

Catalano A, Luo W, Wang Y, O'Day DH
2010, Peptides, 31, 1799-805, 20624437

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2009

Determining time of death: temperature-dependent postmortem changes in calcineurin A, MARCKS, CaMKII, and protein phosphatase 2A in mouse

Poloz YO, O'Day DH
2009, International journal of legal medicine, 123, 305-14, 19326139

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2008

An EGF-like peptide sequence from Dictyostelium enhances cell motility and chemotaxis

Huber R, O'Day DH
2009, Biochemical and biophysical research communications, 379, 470-5, 19121290

Differentiation inducing factor-1 (DIF-1) induces gene and protein expression of the Dictyostelium nuclear calmodulin-binding protein nucleomorphin

O'Day DH, Poloz Y, Myre MA
2009, Cellular signalling, 21, 317-23, 19000924

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2007

Calmodulin-binding proteins in the model organism Dictyostelium: a complete & critical review

Catalano A, O'Day DH
2008, Cellular signalling, 20, 277-91, 17897809

The value of animations in biology teaching: a study of long-term memory retention

O'Day DH
2007, CBE life sciences education, 6, 217-23, 17785404

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2006

Isolation, characterization, and bioinformatic analysis of calmodulin-binding protein cmbB reveals a novel tandem IP22 repeat common to many Dictyostelium and Mimivirus proteins

O'Day DH, Suhre K, Myre MA, Chatterjee-Chakraborty M, Chavez SE
2006, Biochemical and biophysical research communications, 346, 879-88, 16777069

Animated cell biology: a quick and easy method for making effective, high-quality teaching animations

O'Day DH
2006, CBE life sciences education, 5, 255-63, 17012217

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2005

An N-terminal nuclear localization sequence but not the calmodulin-binding domain mediates nuclear localization of nucleomorphin, a protein that regulates nuclear number in Dictyostelium

Myre MA, O'Day DH
2005, Biochemical and biophysical research communications, 332, 157-66, 15896312

Isolation and characterization of Dictyostelium thymidine kinase 1 as a calmodulin-binding protein

O'Day DH, Chatterjee-Chakraborty M, Wagler S, Myre MA
2005, Biochemical and biophysical research communications, 331, 1494-502, 15883042

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2004

Dictyostelium nucleomorphin is a member of the BRCT-domain family of cell cycle checkpoint proteins

Myre MA, O'Day DH
2004, Biochimica et biophysica acta, 1675, 192-7, 15535983

Calmodulin binds to and inhibits the activity of phosphoglycerate kinase

Myre MA, O'Day DH
2004, Biochimica et biophysica acta, 1693, 177-83, 15363631

Dictyostelium calcium-binding protein 4a interacts with nucleomorphin, a BRCT-domain protein that regulates nuclear number

Myre MA, O'Day DH
2004, Biochemical and biophysical research communications, 322, 665-71, 15325281

Calmodulin-binding domains in Alzheimer’s disease proteins: extending the calcium hypothesis

O'Day DH, Myre MA
2004, Biochemical and biophysical research communications, 320, 1051-4, 15249195

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2003

Protein kinase Calpha negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor

Gauthier ML, Torretto C, Ly J, Francescutti V, O'Day DH
2003, Biochemical and biophysical research communications, 307, 839-46, 12878187

CaMBOT: profiling and characterizing calmodulin-binding proteins

O'Day DH
2003, Cellular signalling, 15, 347-54, 12618209

Post-mortem changes in calmodulin binding proteins in muscle and lung

Kang S, Kassam N, Gauthier ML, O'Day DH
2003, Forensic science international, 131, 140-7, 12590053

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2002

Nucleomorphin. A novel, acidic, nuclear calmodulin-binding protein from dictyostelium that regulates nuclear number

Myre MA, O'Day DH
2002, The Journal of biological chemistry, 277, 19735-44, 11919178

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