Professor Mounir G. AbouHaidar

Mounir G. AbouHaidar



St. George (downtown)

CSB Appointment


Research Areas

Biotechnology, Genetics / Genomics, Microbiology, Molecular Biology


Ph.D. D.S. University of Strasbourg, France 1973 & 1976
M.Sc. University of Strasbourg, France 1971

Primary Undergraduate Department

Cell & Systems Biology

Graduate Programs

Cell & Systems Biology
Developmental Biology

Research Description

Research interests lie in the area of the molecular biology of plant and human viruses. Development of “”transgenic”” plants resistant to viruses: mechanisms of resistance. Genome organization, self-splicing (Ribozyme) and replication strategies of some viruses and their satellite RNAs. Development of recombinant vaccines produced in plants. Plant antiviral proteins for gene therapy of AIDS. Molecular mechanisms involved in the translation in Pro- and Eukaryotes: alternative modes of initiation of translation. Development of vaccines (e.g. HCV).

Contact Information

Office Phone: 416-978-5615
Office: ESC4057
Lab: ESC4054
Lab Phone: 416-978-5594

Mailing Address

Department of Cell & Systems Biology
University of Toronto
25 Willcocks St.
Toronto, ON M5S 3B2

Recent News

Graduate student excellence recognized in the 2019-2020 Graduate Student Awards

The academic excellence, research potential and leadership abilities of Cell & Systems Biology graduate students was recognized in award…

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The CSB Forefront is a fascinating digital magazine produced by CSB graduate students

The inaugural volume of Cell & Systems Biology's graduate student newsletter is out! The CSB Forefront covers many aspects of life in grad…

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Polyvalent immunization elicits a synergistic broadly neutralizing immune response to hypervariable region 1 variants of hepatitis C virus

Mosa A, Campo D, Khudyakov Y, AbouHaidar M, Gehring A, Zahoor A, Ball J, Urbanowicz R, Feld J
2023, Proceedings of the National Academy of Sciences, 10.1073/pnas.2220294120

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Combating Human Viral Diseases: Will Plant-Based Vaccines Be the Answer?

Venkataraman S, Hefferon K, Makhzoum A, Abouhaidar M
2021, Vaccines, 10.3390/vaccines9070761

Novel approaches to circumvent the devastating effects of pests on sugarcane

Qamar Z, Nasir IA, Abouhaidar MG, Hefferon KL, Rao AQ, Latif A, Ali Q, Anwar S, Rashid B, Shahid AA
2021, Scientific Reports, 10.1038/s41598-021-91985-8

A risk progression breast epithelial 3D culture model reveals Cx43/hsa_circ_0077755/miR-182 as a biomarker axis for heightened risk of breast cancer initiation

Naser Al Deen N, Atallah Lanman N, Chittiboyina S, Lelièvre S, Nasr R, Nassar F, Zu Dohna H, AbouHaidar M, Talhouk R
2021, Scientific Reports, 10.1038/s41598-021-82057-y

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Molecular interactions of plant viral satellites

Badar U, Venkataraman S, AbouHaidar M, Hefferon K
2020, Virus Genes, 10.1007/s11262-020-01806-9

A bivalent HCV peptide vaccine elicits pan-genotypic neutralizing antibodies in mice

Mosa AI, Urbanowicz RA, AbouHaidar MG, Tavis JE, Ball JK, Feld JJ
2020, Vaccine, 10.1016/j.vaccine.2020.08.066

Role of HVR1 sequence similarity in the cross-genotypic neutralization of HCV

Mosa AI, AbouHaidar MG, Urbanowicz RA, Tavis JE, Ball JK, Feld JJ
2020, Virology Journal, 10.1186/s12985-020-01408-9

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How Computational Epitope Mapping Identifies the Interactions between Nanoparticles Derived from Papaya Mosaic Virus Capsid Proteins and Immune System

Zamani-Babgohari M, Hefferon KL, Huang T, AbouHaidar MG
2019, Current Genomics, 10.2174/1389202920666190527080230

Connexin43 as a Tumor Suppressor: Proposed Connexin43 mRNA-circularRNAs-microRNAs Axis Towards Prevention and Early Detection in Breast Cancer

Naser Al Deen N, AbouHaidar M, Talhouk R
2019, Frontiers in Medicine, 10.3389/fmed.2019.00192

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Virus-Based RNA Silencing Agents and Virus-Derived Expression Vectors as Gene Therapy Vehicles

Venkataraman S, Ahmad T, AbouHaidar MG, Hefferon KL
2017, Recent Patents on Biotechnology, 10.2174/1872208311666170301103722

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Recent Patents in Oncolytic Virotherapy

Ahmad T, Venkataraman S, AbouHaidar M, L. Hefferon K
2016, Recent Patents on Biotechnology, 10.2174/187220830902160308183917

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Novel coding, translation, and gene expression of a replicating covalently closed circular RNA of 220 nt

AbouHaidar MG, Venkataraman S, Golshani A, Liu B, Ahmad T
2014, Proceedings of the National Academy of Sciences of the United States of America, 25253891

Viral and chloroplastic signals essential for initiation and efficiency of translation in Agrobacterium tumefaciens

Ahmad T, Venkataraman S, Hefferon K, AbouHaidar MG
2014, Biochemical and biophysical research communications, 452, 14-20, 25117444

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Recent patents involving virus nucleotide sequences; host defense, RNA silencing and expression vector strategies

Ahmad T, AbouHaidar M, Hefferon KL
2011, Recent patents on DNA & gene sequences, 5, 202-13, 21867477

Structural and sequence integrity are essential for the replication of the viroid-like satellite RNA of lucerne transient streak virus

Gellatly D, Mirhadi K, Venkataraman S, AbouHaidar MG
2011, The Journal of general virology, 92, 1475-81, 21346030

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Investigating the in vivo activity of the DeaD protein using protein-protein interactions and the translational activity of structured chloramphenicol acetyltransferase mRNAs

Butland G, Krogan NJ, Xu J, Yang WH, Aoki H, Li JS, Krogan N, Menendez J, Cagney G, Kiani GC, Jessulat MG, Datta N, Ivanov I, Abouhaidar MG, Emili A, Greenblatt J, Ganoza MC, Golshani A
2007, Journal of cellular biochemistry, 100, 642-52, 16983699

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Escherichia coli mRNAs with strong Shine/Dalgarno sequences also contain 5′ end sequences complementary to domain # 17 on the 16S ribosomal RNA

Golshani A, Krogan NJ, Xu J, Pacal M, Yang XC, Ivanov I, Providenti MA, Ganoza MC, Ivanov IG, AbouHaidar MG
2004, Biochemical and biophysical research communications, 316, 978-83, 15044080

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Induction of innate immunity by IL-2-expressing Salmonella confers protection against lethal infection

al-Ramadi BK, Mustafa N, AbouHaidar M, Fernandez-Cabezudo MJ
2003, Molecular immunology, 39, 763-70, 12617991

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Inability of Agrobacterium tumefaciens ribosomes to translate in vivo mRNAs containing non-Shine-Dalgarno translational initiators.

Golshani A, Xu J, Kolev V, Abouhaidar MG, Ivanov IG
2002, Zeitschrift fur Naturforschung. C, Journal of biosciences, 57, 307-12, 12064732

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