Satyaki Rajavasireddy
Assistant Professor
Campus
UTSC
CSB Appointment
Full
Research Areas
Bioinformatics / Computational Biology, Biotechnology, Developmental Biology, Evolutionary Biology, Genetics / Genomics, Molecular Biology, Plant Biology
Education
B.S. Osmania Univeristy, India
M.S. Tata Institute for Fundamental Research, India
Ph.D. from Cornell University
Primary Undergraduate Department
Department of Biological Sciences, UTSC
Graduate Programs
Cell and Systems Biology, Ecology and Evolutionary Biology
Research Description
The long-term goal of our lab is to engineer seeds that are adapted to the fast-changing climate of our planet.
Towards this end, we will be studying seed development with a special emphasis on the endosperm. Endosperm is often essential for seed development and provides more than 60% of humanity’s nutritional needs. Unfortunately, endosperm development is sensitive to environmental stress and climate change induced extreme weather can decimate plant productivity.
To engineer resilient seeds, we need a better understanding of seed development. We will use genetic and genomic tools to identify genetic and epigenetic pathways regulating endosperm development in the model organism A. thaliana. However, seed development evolves rapidly and can sometimes vary between even closely related species. Therefore, to obtain a broader perspective into seed development and in order to translate our work into ecologically and environmentally important species, we will examine how and why the regulation of endosperm development changes between species. Using these perspectives, we will examine how endosperm development changes in response to climate change and engineer climate-change tolerant seeds.
Contact Information
Office: SY246
Lab: SY235
Email
Mailing Address
Department of Biological Sciences
University of Toronto
1265 Military Trail
Scarborough, ON M1C 1A4
Canada
Publications
2022
RNA Pol IV induces antagonistic parent-of-origin effects on Arabidopsis endosperm
Chen X, Satyaki PRV, Gehring M
2022, PLOS Biology, 10.1371/journal.pbio.3001602
2020
Water lily ( Nymphaea thermarum ) genome reveals variable genomic signatures of ancient vascular cambium losses
Povilus RA, DaCosta JM, Grassa C, Satyaki PRV, Moeglein M, Jaenisch J, Xi Z, Mathews S, Gehring M, Davis CC, Friedman WE
2020, Proceedings of the National Academy of Sciences, 10.1073/pnas.1922873117
2019
Paternally Acting Canonical RNA-Directed DNA Methylation Pathway Genes Sensitize Arabidopsis Endosperm to Paternal Genome Dosage
Satyaki PR, Gehring M
2019, The Plant Cell, 10.1105/tpc.19.00047
2018
A variably imprinted epiallele impacts seed development
Köhler C, Pignatta D, Novitzky K, Satyaki PRV, Gehring M
2018, PLOS Genetics, 10.1371/journal.pgen.1007469
2017
DNA methylation and imprinting in plants: machinery and mechanisms
Satyaki PRV, Gehring M
2017, Critical Reviews in Biochemistry and Molecular Biology, 10.1080/10409238.2017.1279119
A Small RNA Pathway Mediates Allelic Dosage in Endosperm
Erdmann RM, Satyaki PR, Klosinska M, Gehring M
2017, Cell Reports, 10.1016/j.celrep.2017.11.078
2016
Endosperm and Imprinting, Inextricably Linked
Gehring M, Satyaki P
2016, Plant Physiology, 10.1104/pp.16.01353
2014
The Hmr and Lhr Hybrid Incompatibility Genes Suppress a Broad Range of Heterochromatic Repeats
Malik HS, Satyaki PRV, Cuykendall TN, Wei KH, Brideau NJ, Kwak H, Aruna S, Ferree PM, Ji S, Barbash DA
2014, PLoS Genetics, 10.1371/journal.pgen.1004240
A Screen for F1 Hybrid Male Rescue Reveals No Major-Effect Hybrid Lethality Loci in theDrosophila melanogasterAutosomal Genome
Cuykendall TN, Satyaki P, Ji S, Clay DM, Edelman NB, Kimchy A, Li L, Nuzzo EA, Parekh N, Park S, Barbash DA
2014, G3 Genes|Genomes|Genetics, 10.1534/g3.114.014076
2012
How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways
Ferree PM, Prasad S
2012, Genetics Research International, 10.1155/2012/430136