Course: Foundational Discoveries in Genome Biology and Bioinformatics: Alphafold and it’s Implications

Course Code: CSB 1482H/F, Teaching Section LEC 0101

Coordinator

Professor Alan Moses

Offered Fall 2026 session

Enrolment limited to 6 graduate students (minimum 3 reserved for CSB grads)

Weight

Half credit (0.5 FCE)

Time

Tuesdays 11 am – 1 pm

Location

RW-142, St. George campus (Ramsay Wright Building)

*CSB 1482H/F is a half-credit course that takes place during the full Fall session.  It is the equivalent of two modules.  This course is also offered to undergraduate students as CSB 471H1F.  Graduate students should NOT request this course as CSB471H1F on ACORN because it would not count toward graduate credit.

Course Description

This course will focus on close reading and detailed discussion of landmark papers in the area of computational protein structure prediction, centered around the breakthrough of AlphaFold2. Focus will be on the context of the paper, technological developments exploited (or reported) and impact on the field. Topics include: evolutionary co-variation, neural networks, protein structure databases, and research applications of protein structure prediction.

Evaluation

In-class quizzes 40%
Independent research report 30%
Discussion/participation 30%

Pre-requisites

Instructor approval

Last updated on June 24th, 2026