Synthetic-Biology-Probiotic-1

June 29, 2021
|By Neil Macpherson

Human P2Y2 is a GPCR protein that responds to eATP. In a yeast synthetic biology circuit,, P2Y2 activates transcription of potato apyrase, which reduces eATP levels when secreted. This sense and respond circuit may reduce IBD when used in a probiotic yeast. Figure created with BioRender.com

Human P2Y2 is a GPCR protein that responds to eATP. In a yeast synthetic biology circuit,, P2Y2 activates transcription of potato apyrase, which reduces eATP levels when secreted. This sense and respond circuit may reduce IBD when used in a probiotic yeast. Figure created with BioRender.com