Course Description

This is an in-depth examination of the unique cellular adaptations of different organisms and tissues to survival in low oxygen environments. Biochemical, cellular, and physiological strategies, and systemic and whole organism responses will be investigated to uncover broad-ranging common strategies employed by diverse organisms to live without oxygen and in other stressful environments.

Schedule:

Lectures: Examples of cellular, physiological and biochemical strategies employed by diverse organisms to live without oxygen and in other stressful environments to uncover common strategies.

Seminar: in groups of 2 to 4, students will present a Journal Club style seminar to the class based upon their assigned paper.

Midterm Writing Assignment: based upon their assigned paper, students will write a News and Views style article.

The topics will be subdivided into 3 sections:

  1. Control of Energy Metabolism
  2. Biochemical Adaptations to Stressful Environments
  3. Cellular Oxygen Sensing

Prerequisite

(BIO270H1, BIO271H1) / (PSL300H1, PSL301H1)

Exclusion

CSB347H1,
NUS348H0

Recommended preparation

BCH210H1

Lecturer(s)

Prof. L. Buck
les.buck@utoronto.ca

Contact Hours

18L, 18S

Required Text(s)/Readings

Readings will be posted on Quercus at the beginning of the course.

Evaluation (Subject to change)

Midterm Writing Assignment (News & Views style): 30%
Journal Club Presentation: 30%
In-class participation: 10%
Final Term Test: 30%

Last updated on May 20th, 2021