Striving for Innovative Discoveries Yields Crucial Funding for CSB in 2021

The Department of Cell and Systems Biology, (CSB) here at the University of Toronto is striving towards innovative insights in the field of molecular sciences and systems biology. Our research projects include neurological development, cancer, fundamentals of transcriptional regulation and much…

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Cell wall success with two awards for the McFarlane lab at CSPB 2021!

Our colleagues Natalie Hoffmann and Eduardo Ramirez-Rodriquez won awards for their research on cell wall biosynthesis at the annual Canadian Society of Plant Biologists (CSPB) meeting, held virtually on Nov 27, 2021. Congratulations! For plants, we often consider nutrients inside plant cells to be…

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Tropepe lab reveals reduced photoreceptor integrity underlying Usher Syndrome

Dr Amanda Miles of the Tropepe lab shows that "Usher syndrome type 1-associated gene, pcdh15b, is required for photoreceptor structural integrity in zebrafish" in the Dec 2021 issue of Disease Models & Mechanisms (DMM). Zebrafish protocadherin-15b (pcdh15b) is closest in sequence to the human…

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Congratulations to CSB’s Graduate Student Award Recipients!

Congratulations to our Graduate Students who earned recognition for their accomplishments at our Graduate Student Awards on December 10th, 2021! Valerie Anderson Graduate Fellowship Awarded for academic merit to an outstanding student in any subdiscipline of plant biology. Recipient: Matthew…

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Plotnikov lab finds key to reducing (cellular) stress is spikes of mDia1

When you’re dancing, running or even walking, fibroblast cells stretch and adapt to all your vigorous movements. What allows these dynamic cells in our bodies to keep their shape and position without being torn apart? Fernando Valencia in Sergey Plotnikov’s lab at Cell & Systems Biology has…

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What Sits at the Centre of Wound Healing?

The science of rapid wound healing has new insights due to discoveries in fruit flies from the Fernandez-Gonzalez lab at University of Toronto. The results of their collaboration, community and perseverance were published in the journal Cell Reports as “p38-mediated cell growth and survival drive…

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Sugar-coated cells’ surprise role in gastrulation

The way embryonic cells stick to each other is given a new twist by studies of the sugar coating around developing tissues. The Winklbauer lab has shown that the glycocalyx sugar coat mediates cell-cell attachment across significantly large distances between cells. These surprising results are…

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Calarco Lab receives Connaught Award to map RNA binding proteins in the nervous system

Professor John Calarco has been granted a Connaught New Researcher Award to publish a detailed atlas of RNA binding proteins (RBPs), key regulators of gene expression, in the nervous system of the roundworm C. elegans. Mutations in RBP genes are thought to be associated with diseases including…

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Sustainability in the Earth Sciences Centre

Settled on top of UofT’s Earth Sciences Centre on Huron Street are fifteen greenhouse zones for CSB and EEB researchers. High energy sodium lamps provide light to grow cultivated plants, but a new sustainability project is underway to replace these lamps with energy efficient LEDs. The Earth…

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Push and pull – the forces that earn Sergey Plotnikov a prestigious CIHR grant

Prof Sergey Plotnikov studies how cell movement is guided by the stiffness of the tissue around the cell, and a new CIHR grant will allow his lab to continue pushing this work forward. Each day, cells in our body are continuously bombarded by a myriad of biological signals. As you are comfortably…

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