Dorothea Godt

Associate Professor


Campus

St. George (downtown)

CSB Appointment

Full

Research Areas

Animal Biology, Cell Biology, Developmental Biology, Genetics / Genomics, Molecular Biology

Education

Postdoctoral research 1991-1996, UCLA, USA
Ph.D. 1990, University of Cologne, Germany
Diploma 1985, Lud. Max. University Munich, Germany

Primary Undergraduate Department

Cell & Systems Biology

Graduate Programs

Cell & Systems Biology
Developmental Biology

Research Description

Analysis of molecular networks that drive cell shape changes, cell migration, and cell and tissue architecture during animal development


Contact Information

Office Phone: 416-978-8714
Office: RW608A
Lab: RW608/RW609
Lab Phone: 416-946-3691
Email

Mailing Address

Department of Cell & Systems Biology
University of Toronto
25 Harbord St.
Toronto, ON M5S 3G5
Canada

Visit lab’s website


Publications

2020

Integration of Migratory Cells into a New Site In Vivo Requires Channel-Independent Functions of Innexins on Microtubules

Miao G, Godt D, Montell DJ
2020, Developmental Cell, 10.1016/j.devcel.2020.06.024

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2018

Dissection and Staining of Drosophila Pupal Ovaries

Park KS, Godt D, Kalderon D
2018, Journal of Visualized Experiments, 10.3791/56779

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2017

Specification and spatial arrangement of cells in the germline stem cell niche of the Drosophila ovary depend on the Maf transcription factor Traffic jam

Xie T, Panchal T, Chen X, Alchits E, Oh Y, Poon J, Kouptsova J, Laski FA, Godt D
2017, PLOS Genetics, 10.1371/journal.pgen.1006790

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2016

The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals

Li T, Giagtzoglou N, Eberl DF, Jaiswal SN, Cai T, Godt D, Groves AK, Bellen HJ
2016, eLife, 10.7554/eLife.15258

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2015

Loss of SPARC dysregulates basal lamina assembly to disrupt larval fat body homeostasis inDrosophila melanogaster

Shahab J, Baratta C, Scuric B, Godt D, Venken KJ, Ringuette MJ
2015, Developmental Dynamics, 10.1002/dvdy.24243

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2014

Loss of SPARC dysregulates basal lamina assembly to disrupt larval fat body homeostasis in Drosophila melanogaster

Shahab J, Baratta C, Scuric B, Godt D, Venken KJ, Ringuette MJ
2014, Developmental dynamics : an official publication of the American Association of Anatomists, 25529377

Myosin VIIA regulates microvillus morphogenesis and interacts with cadherin Cad99C in Drosophila oogenesis

Glowinski C, Liu RH, Chen X, Darabie A, Godt D
2014, Journal of cell science, 127, 4821-32, 25236597

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2013

The Maf factor Traffic jam both enables and inhibits collective cell migration in Drosophila oogenesis

Gunawan F, Arandjelovic M, Godt D
2013, Development (Cambridge, England), 140, 2808-17, 23720044

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2012

Mutational analysis supports a core role for Drosophila α-catenin in adherens junction function

Sarpal R, Pellikka M, Patel RR, Hui FY, Godt D, Tepass U
2012, Journal of cell science, 125, 233-45, 22266901

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2009

Breaking a temporal barrier: signalling crosstalk regulates the initiation of border cell migration

Godt D, Tepass U
2009, Nature cell biology, 11, 536-8, 19404334

The germline stem cells of Drosophila melanogaster partition DNA non-randomly

Karpowicz P, Pellikka M, Chea E, Godt D, Tepass U, van der Kooy D
2009, European journal of cell biology, 88, 397-408, 19395121

Cell dynamics and developmental bias in the ontogeny of a complex sexually dimorphic trait in Drosophila melanogaster

Atallah J, Liu NH, Dennis P, Hon A, Godt D, Larsen EW
2009, Evolution & development, 11, 191-204, 19245550

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2008

Expression profile of the cadherin family in the developing Drosophila brain

Fung S, Wang F, Chase M, Godt D, Hartenstein V
2008, The Journal of comparative neurology, 506, 469-88, 18041774

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2007

Integrin-dependent anchoring of a stem-cell niche

Tanentzapf G, Devenport D, Godt D, Brown NH
2007, Nature cell biology, 9, 1413-8, 17982446

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2005

Drosophila melanogaster Cad99C, the orthologue of human Usher cadherin PCDH15, regulates the length of microvilli

D'Alterio C, Tran DD, Yeung MW, Hwang MS, Li MA, Arana CJ, Mulligan VK, Kubesh M, Sharma P, Chase M, Tepass U, Godt D
2005, The Journal of cell biology, 171, 549-58, 16260500

Talin’s second persona

Tepass U, Godt D
2005, Nature cell biology, 7, 443-4, 15867924

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2003

The large Maf factor Traffic Jam controls gonad morphogenesis in Drosophila

Li MA, Alls JD, Avancini RM, Koo K, Godt D
2003, Nature cell biology, 5, 994-1000, 14578908

Hand-me-downs. Transmitting anterior-posterior asymmetry from older to younger egg follicles

Godt D, Tepass U
2003, Developmental cell, 5, 525-7, 14536049

The Drosophila melanogaster BTB proteins bric à brac bind DNA through a composite DNA binding domain containing a pipsqueak and an AT-Hook motif

Lours C, Bardot O, Godt D, Laski FA, Couderc JL
2003, Nucleic acids research, 31, 5389-98, 12954775

Organogenesis: keeping in touch with the germ cells

Godt D, Tepass U
2003, Current biology : CB, 13, R683-5, 12956974

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2002

Cell sorting in animal development: signalling and adhesive mechanisms in the formation of tissue boundaries

Tepass U, Godt D, Winklbauer R
2002, Current opinion in genetics & development, 12, 572-82, 12200163

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