Hone-Buske Award winner Julia Gauberg identifies presynaptic channel homologues in ancient animal

The Christine Hone-Buske award is given each year to a CSB graduate student who has produced an outstanding paper in their field. This year, the award went to PhD candidate Julia Gauberg for her publication “Conserved biophysical features of the CaV2 presynaptic Ca2+ channel homologue from the…

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Resurrected proteins reveal evolutionary history of Amazon River fish

As the Andes mountains were rising 15-20 million years ago, the freshwater Amazon basin became flooded with seawater. This event provided an opportunity to adapt to a freshwater habitat for marine species carried along with the seawater. University of Toronto Professors Belinda Chang and Nathan…

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Collaboration is key at CSB’s aquatic research facility

Amanda Miles’ PhD studies in Prof Vince Tropepe’s lab focus on the development, maintenance, and degeneration of the retina. “The eye is extremely complex; if you stop and think about how your eye develops properly and what allows you to see the vast wonders surrounding you- it’s incredible!…

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CSB Year in Review: Top Stories of 2020

As the year comes to a close, we look back on the achievements of students, staff, and faculty in the Cell and Systems Biology Department. Here are some of the top CSB stories of 2020. Research discoveries in CSB In 2020, researchers in the Cells and Systems Biology Department made strides with…

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Alan Moses decodes and remodulates proteins to earn Canada Research Chair

Professor Alan Moses of Cell & Systems Biology is at the forefront of data science in cracking the lingering mysteries underlying the function of protein molecules. He has been renewed for his position as Canada Research Chair (CRC), recognizing that he will be leading further advances in his…

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Splicing and remixing coded cellular messages reveals new controls on nervous system development.

The Calarco lab in Cell & Systems Biology at U of T has unveiled the signals that direct how RNA messages are remixed within the diverse organs of an animal in a new publication “Global regulatory features of alternative splicing across tissues and within the nervous system of C. elegans”. When…

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In Memoriam: Professor Betty Ida Roots

The University of Toronto Community lost an eminent scholar on October 24th with the passing of Professor Betty Ida Roots, PhD, DSc, FRSC. She served the University in a number of roles; as Professor at U of T from 1969, Assistant Chair of Zoology beginning in 1972, Associate Dean of Science at UTM…

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Preparing to Push: Epigenetic analysis of uterine muscle cells reveals molecular basis of term labour

Answers to some questions in science require the development of new technologies; molecular biologists once examined selected pieces of DNA and the proteins that bound them, but advances in computation and instrumentation mean biologists can now determine where proteins bind across the whole…

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Breaking barriers: Quebec platelet disorder

A decade after the discovery that Quebec Platelet Disorder is caused by a tandem duplication, the Mitchell laboratory and collaborators demonstrate that this causes the additional copy of the duplicated PLAU gene to be on the opposite side of a CTCF genomic boundary. As a consequence, the extra…

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Building excellence in research and teaching: CSB’s new Chair Nicholas Provart

Professor Nick Provart likes building things; he even used his carpentry skills to expand his children’s treehouse while working from home (without losing any fingers). As the new Chair of the Department of Cell & Systems Biology (CSB), he now has the opportunity to build up the academic…

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