Guzzo lab assesses UV technology to inactivate HIV-1 and hCoV-229E

Prof Christina Guzzo's lab has published a study in Virology Journal looking at UV treatment to inactivate Human Immunodeficiency Virus and the seasonal human coronavirus 229E. Her students Arvin Persaud and Jonathan Burnie published their results as "A UV-LED module that is highly effective at…

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David G Butler (1936-2022), Professor of Endocrinology

We are sad to share the news that our emeritus Professor David G Butler passed away in February 2022. Born in Vancouver, BC, David Butler obtained his PhD with Professor Ian Chester-Jones at the University of Sheffield in 1964 and was recruited to the Department of Zoology that same year. He began…

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Striving for Innovative Discoveries Yields Crucial Funding for CSB in 2021

The Department of Cell and Systems Biology, (CSB) here at the University of Toronto is striving towards innovative insights in the field of molecular sciences and systems biology. Our research projects include neurological development, cancer, fundamentals of transcriptional regulation and much…

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Cell wall success with two awards for the McFarlane lab at CSPB 2021!

Our colleagues Natalie Hoffmann and Eduardo Ramirez-Rodriquez won awards for their research on cell wall biosynthesis at the annual Canadian Society of Plant Biologists (CSPB) meeting, held virtually on Nov 27, 2021. Congratulations! For plants, we often consider nutrients inside plant cells to be…

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Tropepe lab reveals reduced photoreceptor integrity underlying Usher Syndrome

Dr Amanda Miles of the Tropepe lab shows that "Usher syndrome type 1-associated gene, pcdh15b, is required for photoreceptor structural integrity in zebrafish" in the Dec 2021 issue of Disease Models & Mechanisms (DMM). Zebrafish protocadherin-15b (pcdh15b) is closest in sequence to the human…

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Congratulations to CSB’s Graduate Student Award Recipients!

Congratulations to our Graduate Students who earned recognition for their accomplishments at our Graduate Student Awards on December 10th, 2021! Valerie Anderson Graduate Fellowship Awarded for academic merit to an outstanding student in any subdiscipline of plant biology. Recipient: Matthew…

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Plotnikov lab finds key to reducing (cellular) stress is spikes of mDia1

When you’re dancing, running or even walking, fibroblast cells stretch and adapt to all your vigorous movements. What allows these dynamic cells in our bodies to keep their shape and position without being torn apart? Fernando Valencia in Sergey Plotnikov’s lab at Cell & Systems Biology has…

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What Sits at the Centre of Wound Healing?

The science of rapid wound healing has new insights due to discoveries in fruit flies from the Fernandez-Gonzalez lab at University of Toronto. The results of their collaboration, community and perseverance were published in the journal Cell Reports as “p38-mediated cell growth and survival drive…

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Sugar-coated cells’ surprise role in gastrulation

The way embryonic cells stick to each other is given a new twist by studies of the sugar coating around developing tissues. The Winklbauer lab has shown that the glycocalyx sugar coat mediates cell-cell attachment across significantly large distances between cells. These surprising results are…

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Calarco Lab receives Connaught Award to map RNA binding proteins in the nervous system

Professor John Calarco has been granted a Connaught New Researcher Award to publish a detailed atlas of RNA binding proteins (RBPs), key regulators of gene expression, in the nervous system of the roundworm C. elegans. Mutations in RBP genes are thought to be associated with diseases including…

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