Transcriptional enhancers don’t require ‘master regulators’

A common assumption in studying gene transcription is that there are 'master regulators' that are required for gene regulation. Gurdeep Singh from Professor Jennifer Mitchell’s laboratory challenges this view in the latest Genome Research by showing that gene transcription can be precisely…

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Dr Sakthi Moorthy chasing the dream to be a scientist from India to Canada

For International Women’s Day 2021, Cell & Systems Biology (CSB) is highlighting the scientists behind the science we publish, and the staff that support them. Dr Sakthi Moorthy has been a valued member of the Mitchell Laboratory in CSB, and we would like to congratulate her on her new position…

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CSB Year in Review: Top Stories of 2020

As the year comes to a close, we look back on the achievements of students, staff, and faculty in the Cell and Systems Biology Department. Here are some of the top CSB stories of 2020. Research discoveries in CSB In 2020, researchers in the Cells and Systems Biology Department made strides with…

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Preparing to Push: Epigenetic analysis of uterine muscle cells reveals molecular basis of term labour

Answers to some questions in science require the development of new technologies; molecular biologists once examined selected pieces of DNA and the proteins that bound them, but advances in computation and instrumentation mean biologists can now determine where proteins bind across the whole…

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Breaking barriers: Quebec platelet disorder

A decade after the discovery that Quebec Platelet Disorder is caused by a tandem duplication, the Mitchell laboratory and collaborators demonstrate that this causes the additional copy of the duplicated PLAU gene to be on the opposite side of a CTCF genomic boundary. As a consequence, the extra…

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Prestigious National Award for CSB PhD Graduate Navroop Dhaliwal

Congratulations to recent CSB graduate Navroop Dhaliwal, for receiving the Graduate Student Research Prize from the Canadian Council of University Biology Chairs. Dr Dhaliwal's research in Professor Mitchell's laboratory provided a significant new insight into the very first steps taken by stem…

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